摘要
目的:了解自然流产妇女的甲状腺功能状态。方法:以2007年1月～2009年2月在本中心就诊的自然流产妇女作为病例组,并在本地选择已有正常生育经历,无任何不良产史同年龄女性作为对照组。采用电化学免疫分析法检测其甲状腺功能,包括血清促甲状腺素(TSH)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、抗甲状腺过氧化物酶抗体(TPOAb),并对异常者给予干预治疗。结果:病例组与对照组妇女血清TSH、FT3、TPOAb平均值差异经秩和检验比较有统计学意义。多元回归分析结果表明自然流产发生与有无人工流产史以及妊娠次数具有相关性。结论:诊治育龄妇女临床或者亚临床甲减,减少其妊娠及人工流产次数对预防自然流产发生有重要意义。
Objective：To explore the thyroid function of the women experiencing spontaneous abortion. Methods：The women who sought medical care for spontaneous abortion between January 2007 and February 2009 were recruited as the study group. Those who had normal childbirth experience were enrolled as the control group. The electrochemical-immunoassay method was used to evaluate the thyroid function,including thyroid stimulating hormone （TSH）,free triiodothyronine （FT3）,and free thyroxine （FT4）,thyroid peroxidase antibody （TPOAb）. The relevant treatments were conducted on those who had abnormal results. Results：There were significant differences in the mean concentrations of TSH,FT3,TPOAb between the study group and the control group. The occurrence of spontaneous abortion had relation to induced abortion history and the number of pregnancies. Conclusion：It is of far reaching importance to spontaneous abortion prevention that clinical and subclinical hypothyroidism should be diagnosed and treated as soon as possible,and the number of pregnancies and induced abortion should be reduced as well.
出处
《中国计划生育学杂志》
北大核心
2010年第8期481-483,共3页
Chinese Journal of Family Planning
基金
山东省人口计生委(2008年第9号)
关键词
育龄妇女
自然流产
甲状腺功能
临床研究
Women of reproductive age
Spontaneous abortion
Thyroid function
Clinical research
