摘要
目的:分析补阳还五汤治疗血管性痴呆的疗效和不良反应。方法:以血管性痴呆患者为研究对象、与补阳还五汤比较治疗效果的随机对照试验,评价纳入研究的质量,并用RevMan4.3.2软件进行Meta分析。结果:补阳还五汤治疗血管性痴呆患者总体疗效优于西药。其汇总OR1.71(95%CI1.15～2.53);在提高MMSE、HDS评分方面,补阳还五汤的效果较西药好,汇总WMD分别为1.60(95%CI0.16～3.03)、2.98(95%CI2.34～3.62),未发现明显不良反应。结论:补阳还五汤治疗血管性痴呆在总体疗效方面由于分析结果存有异质性,故无临床意义;在提高MMSE、HDS评分方面有比西药治疗更加有效的倾向,但尚需更多高质量的研究以增加证据的强度。
Objective：To analyze the efficacy and adverse reactions of BuYang HuanWu Decoction（BYHWD） in the treatment of vascular dementia.Methods：Compared with BYHWD treatment of randomized controlled trials and subjected all patients with vascular dementia,the quality included studies were evaluated and RevMan 4.3.2 software was used for Meta analysis.Results：BYHWD was more effective than Western medicine in the treatment of vascular dementia.The summary OR was 1.71（95% CI 1.15 ～ 2.53）;the therapeutic effect of BYHWD was better than Western medicine in improving the MMSE and HDS score.The summary WMD was 1.60（95% CI 0.16 ～ 3.03） and 2.98（95% CI 2.34 ～ 3.62）;there were no obvious adverse reactions.Conclusion：The general efficacy results of BYHWD treating vascular dementia is not clinical significance because there is heterogeneity.BYHWD was more effective than western medicine in improving the MMSE and HDS score,but need more high-quality research in order to increase the strength of the evidence.
出处
《甘肃中医》
2010年第8期14-16,共3页
Gansu Journal of Traditional Chinese Medicine
关键词
痴呆
血管性
中医疗法
系统评价
META分析
vascular dementia
chinese medical treatments
systematic reviews
meta analysis
