摘要
肺炎支原体是社区获得性肺炎的常见病原体之一,一年四季均可发病.严重感染者可引起多器官损伤、脑炎,甚至导致死亡.目前大环内酯类抗生素是治疗儿童支原体感染的首选药物,但近年来国内外均报道其耐药现象逐渐增加.现将肺炎支原体对于大环内酯类耐药现象、耐药机制和耐药基因检测现状及展望作一综述.
Mycoplasma pneumoniae is one of common pathogens in community-acquired pneumonia. Serious infected patients can have multiple organ injury, encephalitis and even death. Now macrolide antibiotics are choice drugs used for treatment of mycoplasma infection in children, but it is reported that drug resistance has been increasing in recent years. This article reviews macrolide resistance, mechanisms of drug resistance,and status and prospects of drug resistance gene detection of Mycoplasma pneumoniae.
出处
《国际呼吸杂志》
2010年第16期989-993,共5页
International Journal of Respiration
关键词
肺炎支原体
大环内酯类抗生素
耐药
基因检测
Mycoplasma pneumoniae
Macrolide antibiotics
Drug resistance
Gene detection
