摘要
目的：筛选雪莲果片处方及铺料的用量。方法：采用正交试验法,以硬度、吸湿量、口感为考察指标,多指标综合评分进行直观分析,对雪莲果片处方进行优选。结果：雪莲果片处方由雪莲果粉20g、淀粉10g、微晶纤维素15g、羟丙基纤维素15g等组成,可采用湿法制粒压片法制备。结论：处方组成及制备工艺科学合理,稳定性好,硬度、脆碎度、吸湿量等检查合格。
Objective：To screen the formulation of Yacon tablets and the dosage of its excipients.Methods：The orthogonal design was taken to screen formulation of Yacon tablets,the condition were selected by hardness,moisture pickup and taste.Results： formulation of Yacon tablets was 20g of Yacon powder,10g of starch,15g of microcrystalline cellulose,15g of hydroxypropyl cellulose.Wet granulation could be used.Conclusion：The formulation and preparation is rationable,scientific and the stability,hardness,breakage,moisture pickup of the production are qualified.
出处
《大理学院学报（综合版）》
CAS
2010年第6期93-95,共3页
Journal of Dali University
基金
大理学院大学生科研课题药学院立项资助项目(2009DXSKY04)
关键词
雪莲果
正交试验
制备工艺
质量检查
yacon
orthogonal test
preparation process
quality inspection
