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55例子宫内膜癌伴子宫下段受累的临床评价 被引量:2

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摘要 目的探讨子宫内膜癌伴子宫下段受累(LUSI)的临床病理特征,评价LUSI能否作为子宫内膜癌的预后相关因素。方法回顾性分析初治治疗为手术治疗的207例子宫内膜癌患者,按有无LUSI分为2组。比较2组的临床病理特征及预后。结果 LUSI组占全部病例的26.57%(55/207),与对照组(无LUSI)相比较更容易出现低组织学分级、肌层浸润、宫颈受累、脉管浸润及盆/腹腔淋巴结转移,手术病理分期较高(P<0.05),5年生存率较低(P<0.05)。单因素回归分析显示子宫内膜癌侵犯下段可作为预后的不良因素,但Cox比例风险回归模型多因素分析显示,LUSI不是独立的预后相关因素,仅有组织分级、病理类型、脉管浸润以及手术病理分期为子宫内膜癌独立的预后相关因素。结论 LUSI有其特殊的临床病理特征,在子宫内膜癌中并不少见。LUSI通过增加预后不良的高危因素而影响预后,故LUSI可作为子宫内膜癌的一个高危因素,术中术后应予以重视并给予相应的治疗。
作者 江静颖 张晔
出处 《实用临床医药杂志》 CAS 2010年第7期80-82,共3页 Journal of Clinical Medicine in Practice
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同被引文献9

  • 1秦贇娜,钟传庆,于晓红,魏宝秀,付秋风,孙丽萍.子宫浆液性乳头状癌24例临床病理分析[J].临床与实验病理学杂志,2006,22(3):315-319. 被引量:6
  • 2单波儿,王华英,任玉兰,等.术前子宫内膜活检、-1血清CA水平和MRI检查在评估子宫内膜癌淋巴结转移中的价值研究[C]//中国抗癌协会妇科肿瘤专业委员会第十一届全国学术会议论文汇编.2011:237-238.
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  • 5Zehavi S, Schneider D, Bukovsky I, et al. Pathological findings in early-stage endometrial cancer [ J ]. Eur J Gynaecol Oncol, 2003,24( 1 ) :18-20.
  • 6单波儿,王华英,任玉兰,等.术前子宫内膜活检、血清CA水平和MRI检查在评估子宫内膜癌淋巴结转移中的价值研究[G]//中国抗癌协会妇科肿瘤专业委员会第十一届全国学术会议论文汇编.2011:237-238.
  • 7贾军民,刘向芳.子宫内膜癌58例临床病理分析[J].中国药物与临床,2010,10(4):459-460. 被引量:1
  • 8杨琼,刘剑羽,苏静.子宫腺肌瘤与子宫平滑肌瘤3.0T MRI征象对比分析[J].中国医学影像技术,2011,27(1):139-142. 被引量:18
  • 9李蕾,李群.子宫内膜浆液性乳头状癌的诊断及治疗研究进展[J].实用癌症杂志,2012,27(1):103-106. 被引量:3

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