摘要
目的:分析我院药品不良反应(ADR)发生的特点及一般规律,促进安全用药。方法:对我院2009年上报的115例ADR报告,分别从患者性别、年龄、给药途径、引起ADR的药物种类、涉及的器官或系统以及临床表现进行统计、分析。结果:115例ADR报告中,20～39岁的患者ADR发生率最高50.5%;静脉注射比其他给药途径更易发生ADR(96例,占83.5%),抗菌药物引发的ADR比例最高(61例,53.0%),其次为中药制剂(23例,20.0%),头孢菌素类是引发ADR的主要抗菌药物(28例,占45.9%)。ADR最常见的临床表现为皮肤及其附件损害(占80.9%)。结论:应加强ADR监测意识,保证用药安全、有效。
OBJECTIVE：To analyze the features and general patterns of adverse drug reactions （ADRs） occurred in our hospital so as to promote safe medication.METHODS：115 ADR case reports collected in our hospital in 2009 were analyzed statistically in respect of patients＇age and sex,route of administration,drug categories,organs and systems involved and clinical manifestations.RESULTS：Of the 115 ADR cases,50.5% occurred in patients aged between 20 and 39 years.The ADR were more likely induced via intravenous drip infusion （96 cases/83.5% ）.Anti-infectives had the highest proportion with 61cases （53.0% ）,followed by traditional Chinese medicine preparations （23 cases/20.0% ）.Cephalosporins were the leading anti-infective drugs causing ADR （28 case/45.9% ）.80.9% of the ADRs manifested as lesions of skin and its appendants.CONCLUSION：Awareness on ADR monitoring should be strengthened to ensure safe and effective medication.
出处
《中国医院用药评价与分析》
2010年第8期759-760,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
报告
分析
Adverse drug reaction
Report
Analysis
