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β_2-微球蛋白测定在急性白血病中的临床意义 被引量:2

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摘要 目的观察β2-微球蛋白在急性白血病初发、缓解及复发时差异,从而探讨血β2-微球蛋白在急性白血病分期、与预后评价中的临床意义并作为监测疾病活动程度的指标。方法分别对34例急性白血病(AML25例、ALL9例)初发、缓解及复发时的血β2-微球蛋白进行放射免疫竞争抑制法检测。结果急性白血病初发与复发时血β2-微球蛋明显高于正常,初发与复发、复发与缓解者的血β2-微球蛋白水平有显著差异(P<0.05),初发与复发的血β2-微球蛋白水平无显著差异(P>0.05)。结论血β2-微球蛋白在急性白血病初发与复发时增高,随病情缓解而下降,其水平与疾病活动程度成正相关。在急性白血病治疗期间密切观察病情变化,动态监测血β2-微球蛋白水平有助于制定个体化的治疗方案。
出处 《实验与检验医学》 CAS 2010年第4期359-359,370,共2页 Experimental and Laboratory Medicine
基金 景德镇市科学技术局科研项目:景科字[2009]第28号
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