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肝吸虫病患者血清瘦素水平的测定及其意义 被引量:2

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摘要 目的探讨肝吸虫病患者血清中瘦素水平的改变及临床价值。方法采用酶联免疫吸附法(ELISA)检测193例不同类型的肝吸虫病患者和80例正常健康人血清中瘦素水平。结果 95例无症状肝吸虫病患者血清瘦素水平为(7.42±3.15)μg/L;46例胆囊(管)炎的肝吸虫患者血清瘦素水平为(9.89±3.54)μg/L;32例肝硬化肝吸虫病患者血清瘦素水平为(17.26±4.28)μg/L;20例肝癌患者血清瘦素水平为(14.26±4.11)μg/L;80例健康正常对照人群血清瘦素水平为(7.21±2.61)μg/L;显示肝癌患者、肝硬化患者和胆(管)囊炎的肝吸虫患者血清瘦素水平显著高于正常对照组(P<0.01);而无症状的肝吸虫患者血清瘦素水平比正常对照组比较,差别没有显著性意义(P>0.05)。结论不同类型肝吸虫病患者中的血清瘦素水平随着病情程度的逐步加重而升高,提示瘦素可能参与了肝吸虫病的发病及病理过程,血清瘦素的测定有可能作为肝吸虫病患者转归及预后程度判断的一个新指标。
出处 《实验与检验医学》 CAS 2010年第4期361-362,共2页 Experimental and Laboratory Medicine
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