摘要
目的:探讨我院药品不良反应(ADR)发生的特点及一般规律。方法:对我院2008～2009年收集到的3437例ADR报告分别从患者性别、年龄、报告科室、发生时间、给药途径、用药情况、ADR累及器官或系统及临床表现等方面进行统计、分析。结果:3437例ADR报告中,肿瘤科上报最多,有1209例,占35.18%;引发ADR最常见的药物为抗感染药与中药制剂,分别有621、180例;所累及的器官或系统以消化系统损害最为常见,有903例,占26.27%,其次为皮肤及其附件损害,有530例,占15.42%。新的ADR有373例,严重的ADR有743例,其中新的严重的ADR有129例。结论:临床应重视ADR监测,以减少ADR的发生。
OBJECTIVE：To investigate the characteristics and regularity of adverse drug reaction （ADR） occurred in our hospital.METHODS：3 437 ADR cases reported in our hospital between 2008 and 2009 were analyzed statistically in respect of patients＇sex and age,reporting department,onset time,routes of administration,use of drugs,organs and systems involved in ADR and its clinical manifestations,etc.RESULTS：Of 3 437 ADR cases,1 209 cases were submitted by oncology department,accounting for 35.18%.621 cases and 180 cases were caused by anti-infectious agent and traditional Chinese medicine.The most common manifestation of ADR cases were injury of digestive system （903 cases） accounting for 26.27%,followed by lesion of skin and its appendants （530 cases） accounting for 15.42%.There were new ADR of 373 cases,severe ADR of 743 cases and new severe ADR of 129 cases.CONCLUSION：Great importance should be attached to ADR monitoring in order to reduce the incidence of ADR.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第34期3238-3241,共4页
China Pharmacy
