摘要
目的:调研细菌耐药性与抗菌药临床应用的相关性。方法:从本院2007～2009年药库管理记录与细菌室检出细菌耐药情况进行统计分析。结果:抗菌药的使用频度(DDDs)逐年下降,3年总的降幅为16.43%;DDDs保持前4位的是头孢菌素类、β-内酰胺类抗生素的复方制剂、青霉素类及喹诺酮类病原菌的耐药率变化与抗菌药的DDDs密切相关。结论:依患者病原菌动态变化,合理选用抗菌药,能使细菌耐药性降低,达到提高合理用药和治疗水平的目的。
Objective： To Investigation the correlation of drug resistance of bacterial and the clinical application of antimicrobial agents. Method： The pharmacy management records and detected bacteria resistant were statistical analyzed from 2007-2009 in our hospital. Result： The frequency of use antimicrobial drugs （DDDs）was decreased, Three years drop was 16.43%. DDDs maintain 4 digit was Cephaloridine, β-lactamase-producing antibiotics of Compound preparations, Penicillin and Quinolone,The pathogen and the antimicrobial resistant DDDs was closely related. Conclusion ： According to the dynamic changes in patients with reasonable choice of pathogens, reasonable choose antimicrobial agents can reduced bacteria resistant to enhance the rational drug use and treatment level.
出处
《中国药师》
CAS
2010年第9期1317-1320,共4页
China Pharmacist
基金
广东湛江科技攻关项目(编号:2009C3104015)
关键词
细菌耐药性
用药频度(DDDs)
抗菌药
合理用药
Bacterial drug resistance
Drug use frequency（DDDs）
Antibacterials
Rational drug use
