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双极与单极电切术对犬前列腺组织病理学影响的对比研究 被引量:7

Bipolar transurethral resection of the prostate versus monopolar transurethral prostatectomy:A pathological study in a canine model
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摘要 目的:对比研究经尿道前列腺等离子体双极电切术(PKRP)与传统单极前列腺电切术(TURP)术后犬前列腺组织创面凝固层厚度及其病理学的变化。方法:25只成年雄性家犬随机分为3组:PKRP组(12只)、TURP组(12只)和假手术对照组(1只)。于术后0(术后立即)、1、2、8周分别取各组动物处死,获取前列腺标本,光镜下观察前列腺组织病理学改变并测量创面凝固层厚度。结果:术后0、1、2周,PKRP组和TURP组前列腺组织创面的凝固层厚度分别为(237.73±20.12)μm、(113.03±16.65)μm、(106.01±16.36)μm和(200.75±19.34)μm、(129.46±17.81)μm、(116.04±25.67)μm,术后0、1周两组相比,差异有统计学意义(P<0.01)。术后8周,PKRP组和TURP组前列腺组织创面凝固层完全脱落,创面均被覆再生的尿路上皮。术后0、1、2、8周,PKRP组和TURP组前列腺组织均有不同程度的炎症反应,凝固层下部分腺腔扩张,上皮破坏。假手术对照组未见上述变化。结论:PKRP和TURP术对犬前列腺组织创面的病理学影响基本相似。但PKRP术中凝固层厚度大于TURP,提示PKRP术中止血性能可能优于TURP;术后早期,PKRP凝固层较TURP薄,提示PKRP间接的穿透性热损伤可能较TURP小。 Objective :To compare the postoperative depths of the coagulation zones and pathological changes between bipolar transurethral resection of the prostate with plasmakinetic energy (PKRP) and monopolar transurethral prostatectomy (TURP) in canines. Methods :Twenty-five male dogs were randomly divided into a PKRP group (n = 12),a TURP group (n = 12) and a sham-operation control group (n = 1). The dogs were sacrificed,their prostates harvested at 0 week (immediately after surgery),1 week,2 weeks and 8 weeks postoperatively and sectioned for pathologic analysis and measurement of the coagulation zones. Results :At 0,1 and 2 weeks after the operation,the coagulation depths were (237.73±20.12) μm,(113.03±16.65) μm and (106.01±16.36) μm in the PKRP group,and (200.75±19.34) μm,(129.46±17.81) μm and (116.04±25.67) μm in the TURP group (P0.01). At 8 weeks,the coagulation zones completely peeled off and the wounds were covered by regenerated urothelia in both of the groups. At 0,1,2 and 8 weeks,different inflammatory reactions were observed in the prostates of the PKRP and TURP groups,with some glandular lumens beneath the coagulation zones expanded and epithelia damaged. However,none of these phenomena occurred in the sham-operation control group. Conclusion :Pathologically,PKRP and TURP inflicted basically similar effects on the prostate of the canine. However,the coagulation zone was deeper intraoperatively and became thinner postoperatively with the former than with the latter,which suggests that PKRP causes less bleeding and less penetrative thermal damage than TURP.
出处 《中华男科学杂志》 CAS CSCD 北大核心 2010年第8期712-715,共4页 National Journal of Andrology
关键词 双极 经尿道前列腺电切术 前列腺 病理学 bipolar transurethral resection of the prostate pathology dog
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参考文献10

  • 1Botto H, Lebret T, Barre P, et al. Electrovaporization of the prostate with the Gyms device. J Endourol, 2001, 15(3) : 313- 316.
  • 2王行环,王怀鹏,陈浩阳,刘久敏,罗耀雄,冯自卫,罗则民.经尿道等离子体双极电切术治疗良性前列腺增生及膀胱肿瘤[J].中华泌尿外科杂志,2003,24(5):318-320. 被引量:267
  • 3吴伟江,邹伟波,梁晓宇,蔡志高,骆立虎.经尿道等离子体双极电切术治疗良性前列腺增生[J].中国男科学杂志,2005,19(1):30-31. 被引量:17
  • 4Barba M, Leyh H, Hartung R. New technologies in transurethral resection of prostate. Curr Opin Urol, 2000, 10( 1 ) : 9-14.
  • 5Doll HA, Black NA, McPherson K, et al. Mortality, morbidity and complications following transurethral resection of the prostate for benign prostatic hypertrophy. J Urol, 1992, 147 (6) : 1566- 1573.
  • 6de Sio M, Autorino R, Quarto G, et al. Gyrus bipolar versus standard monopolar transurethral resection of the prostate : A randomized prospective trial. Urology, 2006, 67 ( 1 ) : 69-72.
  • 7Wendt-Nordahl G, Hacker A, Fastenmeier K, et al. New bipolar resection device for transurethral resection of the prostate: First ex-vivo and in-vivo evaluation. J Endourol, 2005, 19 (10): 1203 -1209.
  • 8吴伟江,王行环,王怀鹏,邹伟波,梁晓宇,蔡志高,钟巍巍,邹永锋,袁道彰.经尿道等离子体双极电切与经尿道普通电切对前列腺增生症的疗效比较[J].中华医学杂志,2005,85(47):3365-3367. 被引量:104
  • 9Chinpairoj S, Feldman MD, Saunders JC, et al. A comparison of monopolar electrosurgery to a new muhipolar electrosurgical system in a rat model. Laryngoscope, 2001, 111 (2) : 213-217.
  • 10Wang DS, Bird VG, Leonard VV, et al. Use of bipolar energy for transurethral resection of bladder tumors : Pathologic considerations. J Endourol, 2004, 18(6) : 578-582.

二级参考文献19

  • 1Botto H,Lebret T, Barre P, et al. Electrovaporization of prostate with the Gyrus Device. J Endourol,2001,15 : 319-322.
  • 2Ramsey EW. Benign prostatic hyperplasia: a review. Can J Urol,2000,7 : 1135-1143.
  • 3Mebust W, Hohgrewe H, Coeket APC, et al. Transurethral prostectomy: immediate and post operative complication. A comparative study of 13 participating institution evaluating 3 885 patients. J Uro1,1989,141:243-247.
  • 4Virdi J, Kapasi F, Chandrasekar P, et al. A prospective randomized study between transurethral vaporization using plasmakinetic energy and transurethral resection of the prostate. J Urol,2000,163 (4 suppl) :268-269.
  • 5Donovan JL, Peters TJ, Neal DE, et al. A randomized trial comparing transurethral resection of the prostate,laser therapy and conservative treatment of men with symptoms associated with benign pro6tatic enlargement : the CLasP study. J Urol,2000 ,164 :65-70.
  • 6Virdi J, kapasi F, Chandrasekar P, et al. A prospective randomized study between transurethral vaporization using plasmskinetic energy and transurethral resection of the prostate. J Urol 2000; 163(4 suppl): 268-269.
  • 7Botto H, Lebret T, Barre P, et al. Electrovaporization of prostate with the Gyms Device. J Endourol 2001; 15:319-3 22.
  • 8Ramsey EW. Benign prostatic hyperplasia: a review.Can J Urol 2000; 7: 1135-1143.
  • 9Donovan JL Peters TJ, Neal DE, et al. A randomized trial comparing transurethral resection of the prostate,laser therapy and conservative treatment of men with symptoms associated with benign prostatic largement:the ClasP study. J Urol 2000; 164:65-70.
  • 10Mebust W, Holtgrewe H, Cocket APC, et al. transurethral prostectomy:immediate and post operative complication. A comparative study of 13 participating instiution evaluating 3885 patients. J Urol 1989; 141:243-247.

共引文献357

同被引文献52

  • 1刘志文,李解方,丁平,许良余.PKRP和TURP治疗良性前列腺增生的疗效观察[J].南华大学学报(医学版),2005,33(2):216-218. 被引量:7
  • 2赵晓风,孙晓飞,吕志红,王军,刘亮.经尿道前列腺等离子双极电切和经尿道前列腺电切治疗良性前列腺增生的临床结果比较[J].中华泌尿外科杂志,2006,27(9):628-630. 被引量:126
  • 3那彦群.我国良性前列腺增生临床治疗现状及思考[J].中华外科杂志,2007,45(14):937-938. 被引量:23
  • 4Kaplan SA.Benign prostatic hyperplasia[J].J Urol,2011,185(5):1819.
  • 5Dhingra N,Bhagwat D.Benign prostatic hyperplasia:An overview of existing treatment[J].Indian J Phar-macol,2011,43(1):6-12.
  • 6Rocco B,Albo G,Ferreira RC,et al.Recent advancesin the surgical treatment of benign prostatic hyperplasia[J].Ther Adv Urol,2011,3(6):263-272.
  • 7Protogerou V,Kostakopoulos A.Laparoscopic treat-ment of benign prostatic hyperplasia(bph):Overviewof current techniques.Do our patients need it?[J].BJU Int,2011,108(2):8-9.
  • 8Nurmi M.treatment of benign prostatic hyperplasia[J].Duodecim,2011,127(6):601-606.
  • 9Kong CH, |brahi MF, Zainuddin ZM. A prospective, randomized clinical trial comparing bipolar plasma kinetic resection of the prostate versus conventional monopolar transurethral resection of the prostate in the treat- ment of benign prostatic hyperplasia . Ann Saudi Med, 2009,29 : 429- 432.
  • 10Muschter R, Reich O. Surgical and instrumental management of benign pmstatic hyperplasia. Urologea,2008,47 : 155-165.

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