摘要
目的评价结节性硬化症的临床特征和ＣＴ、ＭＲＩ对其诊断价值。方法对１６例结节性硬化症患儿的临床资料进行分析。结果１６例患儿的临床特征为起病年龄３岁以内１５例，占９３％，全部患儿均以癫痫发作为首发症状，有皮肤表现者１３例，占８１％，以色素脱失斑最多见，智力低下者３例，占１９％，全部患儿均有脑ＣＴ或ＭＲＩ改变，对３例不典型病例通过脑ＣＴ检查确诊。结论癫痫、特殊的皮肤损害为本病的主要临床特征，脑ＣＴ或ＭＲＩ检查有助于明确诊断。
Objective To evaluate the clinical
characteristics of tuberous sclerosis complex (TSC) and diagnostic values of computerized
tomography (CT) and magnetic resonance imaging (MRI). Methods The clinical data of 16
children with TSC were studied prospectively. Results TSC in this group of children was
characterized by the age of onset (before 3 years of age in 15 cases), seizure as the first
symptom (in all the cases). skin lesions (in 13 cases). The most common skin lesion was
hypomelanotic macules. Three cases had mental retardation. All patients showed CT or MRI
changes in the brain. CT played an important role in the diagnosis of 3 atypical TSC cases.
Conclusion Epilepsy and special skin lesions were the main clinical characteristics of TSC.CT
or MRI examination could help establish a definite diagnosis.
出处
《中华儿科杂志》
CAS
CSCD
北大核心
1999年第5期291-293,共3页
Chinese Journal of Pediatrics
关键词
儿童
结节性硬化症
癫痫
磁共振成像
CT
诊断
Tuberous
sclerosisEpilepsyTomography, Xray computerizedMagnetic resonance imaging
