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幽门螺杆菌感染对胃窦粘膜TNF-α和PDGF水平的影响 被引量:5

EFFECT OF HELICOBACTER PYLORI INFECTION ON ANTRAL MUCOSAL TUMOR NECROSIS FACTOR-α AND PLATELET-DERIVED GROWTH FACTOR LEVELS
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摘要 检测幽门螺杆菌(HelicobacterPylori,Hp)感染胃炎患者鲁窦粘膜体外培养上消液中肿瘤坏死因子(TumorNecrosisFactor-α,TNF-α)和血小板源生长因子(Platelet-derivedGrowthFactor,PDGF)水平。结果表明,Hp阳性胃炎患者留其粘膜TNF-α含量和PDGF活性均明显高于Hp阴性患者和正常对照组,合并活动性胃炎患者胃窦TNF-α含量和PDGF活性也明显高于非活动性胃炎。 The levels of tumor necrosis factor-α(TNF-α) and Platelet-derived growth factor(PDGF) in human antralmucose of patients with H. Pylori (HP) infection were investigated by radioimmunoassay and bioactivity assay- The resultsshowed that antral TNF-Q and PDGF levels in patients with HP infection were significantly greater than those in patientswithout HP infection and normal controls. TNF-Q level was significantly higher in patients with active gastritis than in thosewith inactive gastritis. In contrast, PDGF activity were raised in both active and inactive gastritis.
机构地区 福州解放军第
出处 《中国人兽共患病杂志》 CSCD 北大核心 1999年第3期57-58,共2页 Chinese Journal of Zoonoses
关键词 幽门螺杆菌 胃窦粘膜 TNF-Α PDGF Helicobacter Pylori Tumor necrosis factor-α Platelet-derived growth factor Gastric mucosa
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参考文献7

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