摘要
目的:通过与传统开颅手术治疗高血压脑出血相比较,探讨显微手术联合纳洛酮治疗高血压脑出血的临床疗效。方法:将符合条件的高血压脑出血病人90例,随机分成三组:A组28例,传统开颅组;B组30例,显微手术组;C组32例,显微手术联合纳洛酮组。治疗前后采用临床神经功能缺损(CSS)程度评分和格拉斯哥预后评分进行疗效判断。结果:治疗后B组与A组疗效差异有显著性(P<0.05),C组与A组疗效差异有显著性(P<0.01),C组与B组疗效差异有显著性(P<0.01)。结论:显微手术治疗高血压脑出血及术后应用纳洛酮,降低了致残率,提高了康复率,疗效明显优于传统开颅和显微手术。
Objective： Through comparing with traditional craniotomy operation,we aimed at exploring the clinical effect of using micro- surgery combined with Naloxone to treat hy- pertensive intracerebral hemorrhage. Meth- ods：We divided the eligible 90 patients suf- fering from hypertensive intracerebral hem- orrhage into three groups at random：tradi- tional craniotomy group of 28 cases was set as Group A;microsurgery group of 30 cases as Group B; microsurgery combined with Naloxone group of 32 cases as Group C. The curative effects of seven days before and af- ter treatment, fourteen days after treatment were graded by using CSS. Three months lat- er compared the efficacy among the three groups based on glasgow outcome score. Re-suhs：The efficacy between B group and A group was significant difference（ P 〈 0. 05 ）, C group and A group effect was significant difference （ P 〈 0. 01 ） , the difference be- tween C group and B group in efficacy was significant （P 〈 0. 01 ）. Conclusions ： Micro- surgical treatment of hypertensive intracere- bral hemorrhage and Naloxone application after operation can reduce the residual rate and improve the recovery rate, superior to the traditional craniotomy and microsurgery significantly.
关键词
高血压脑出血
显微手术
纳洛酮
Hypertensive intracerebral hemorrhage
microsurgery
Naloxone
