摘要
目的：比较和分析急性牙髓炎和牙齿开髓刺激后，牙髓组织中Ｐ物质（ＳＰ）、降钙素基因相关肽（ＣＧＲＰ）的变化。方法：利用免疫组织化学方法观察大鼠牙齿开髓后２ｈ、４ｈ和急性牙髓炎２ｈ、４ｈ组牙髓组织中ＳＰ、ＣＧＲＰ免疫阳性纤维的变化。结果：牙髓炎性及机械损伤性伤害刺激引起牙髓组织ＳＰ／ＣＧＲＰ免疫阳性纤维一致性变化。牙齿开髓及牙髓炎２ｈ、４ｈ组牙髓组织中ＳＰ、ＣＧＲＰ免疫阳性纤维减少。结论：两种刺激均引起牙髓组织内神经末梢释放ＳＰ、ＣＧＲＰ。
Aim: To investigate the change of SP and CGRP in the pulpal tissue with acute pulpitis and after opening of pulp chamber. Method: To observe the change of the SP- and CGRP- immunoreactive fibres in the pulpal tissue of rat by immunohistochemical method. T5HZResults: The changes of SP- and CGRP- immunoreactive fibres in the pulpal tissue were identical in the two noxious stimulations. These fibres decreased at 2h and 4h after stimulations. Conclusion: The two stimulations lead to the release of SP and CGRP from the pulp nervous terminals.
出处
《牙体牙髓牙周病学杂志》
CAS
1999年第2期133-135,共3页
Chinese Journal of Conservative Dentistry
基金
国家自然科学基金
