摘要
近年来分子生物学技术发展迅速,在妇科恶性肿瘤领域,基因诊断技术已广泛应用于基础研究和少量的临床诊治实践中。如人乳头瘤病毒(HPV)DNA检测在宫颈癌筛查中的作用,BRCA1或BRCA2的突变在卵巢癌患者及其家族中的应用,HER2、p53和PTEN在子宫内膜癌Ⅰ型和Ⅱ型鉴别诊断中的应用等。
With the rapid development of molecular techniques in recent years, gene diagnosis technology has been widely used in basic research and a few clinical practice in the field of gynecologic malignant tumors, Such as the applications of HPV DNA in the screening of cervical cancer, HER2, p53 and PTEN in the differential diagnosis of type Ⅰ and type Ⅱ endometrial cancer, BRCA1 or BRCA2 mutations in ovarian cancer patients and their family numbers and soon.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2010年第9期677-680,共4页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
基因诊断
妇科
恶性肿瘤
gene diagnosis
gynecologic
malignant tumor
