摘要
目的了解洋葱伯克霍尔德菌(Burkholderia cepacia,PCE)临床感染特点和耐药现状。方法对2004—2009年从各类临床标本中分离到的55株PCE株用K-B法进行体外药敏试验,并对患者资料进行统计分析。结果分离菌株最多的标本是痰液(87.3%),分离菌株最多的病区是ICU(52.7%),药敏试验结果表明,PCE对大多数抗生素耐药,耐药率较低的药物为头孢他啶(25.5%)、哌拉西林/他唑巴坦(23.6%)和美罗培南(18.2%)。结论 PCE是一种多重耐药菌,临床治疗应结合药敏试验结果,合理选用抗生素。
Objective To investigate the clinical infection and antibiotic resistance of Burkholderia cepacia. Methods A total of 55 B. cepacia strains were isolated from 2004 to 2009. Antibiotic susceptibility testing was carried out using K - B method and the patients＇ data were analyzed. Results Sputum was the main source of B. cepaeia （87. 3 % ） and ICU was the common department （52.7 % ）. Most B. cepacia isolates showed resistance to most of the tested antibiotics. However, less than 30 % of the isolates were resistant to piperacillin - tazobactam （23.6 % ）, ceftazidime （25.5 % ） and meropenem （ 18.2% ）. Conclusion B. cepacia is highly resistant to most antibiotics. Treatment of B. cepacia infection should be based on the results of antibiotic susceptibility testing.
出处
《河北医科大学学报》
CAS
2010年第8期947-949,共3页
Journal of Hebei Medical University
