期刊文献+

垂体肿瘤239例临床特征分析 被引量:19

Clinical features of 239 cases of pituitary adenomas
原文传递
导出
摘要 目的探讨垂体瘤的临床特征及治疗方案。方法回顾性分析福建省立医院自1994年1月至2007年6月间收住的239例垂体瘤患者的临床资料。结果239例垂体腺瘤中,男性93例(38.9%),女性146例(61.1%)。诊断时的平均年龄为(43.8±14.9)岁(范围为3.9~77岁)。依据临床表现、影像学及内分泌检查、免疫组织化学染色所示,催乳素瘤为最常见的肿瘤(26.8%)。手术治疗179例(74.9%),其中经蝶入路108例(60.3%),经额入路71例(39.7%),非手术治疗及随访者60例(25.1%)。结论垂体瘤可表现为内分泌异常、神经系统症状或其他原因行MRI意外发现;催乳素瘤为最常见的肿瘤。 Objective To study clinical feature and therapeutic choice of pituitary adenomas. Methods The clinical data of 239 cases of pituitary adenomas were analyzed. Results Total 93 male and 146 female cases were recruited. The average age was (43.8±14.9) years old (3.9-77 years). Prolaetinomas were the most common pituitary adenomas (26.8%), 179 patients (74.9%) underwent surgery, of which 108 (60.3%) with transsphenoidal approach and 71 (39.7%) transcranial approach. The other 60 cases were treated nonsurgically. Conclusions Pituitary adenomas may present hormonal abnormalities or neurological symptoms. Some adenomas were accidently detected by MRI. Prolactinomas were the most common pituitary adenomas.
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2010年第8期662-665,共4页 Chinese Journal of Endocrinology and Metabolism
关键词 垂体腺瘤 疾病特征 Pituitary adenomas Disease characteristics
  • 相关文献

参考文献19

  • 1Scheithauer BW,Horvath E,Kovacs K,et al.Plurihormonal pituitary adenomas.Semin Diagn Pathol,1986,3:69-82.
  • 2St-Jean E,Blain F,Comtois R.High prolactin levels may be missed by immunoradiometric assay in patients with macroprolactinomas.Clin Endocrinol(Oxf),1996,44:305-309.
  • 3Abrahamson MJ,Snyder PJ.Causes of hyperprolactinemia.Up to Date,2001,9:1-6.
  • 4Arafah BM,Nasrallah MP.Pituitary tumors:pathophysiology,clinical manifesttations and management.Endocr Relat Cancer,2001,8:287-305.
  • 5Paja M,Lucas T,Garcia Uria J,et al.Hypothalamic-pituitary dysfunction in patients with craniopharyngioma.Clin Endocrinol (Oxf),1995,42:467-473.
  • 6Melmed S.The Pituitary.England,Blackwell Publishers,2002.
  • 7李伟,傅震.垂体腺瘤中PCNA蛋白表达的研究[J].临床神经病学杂志,2001,14(3):136-137. 被引量:6
  • 8Yousem DM,Arrington JA,Zinreich SJ,et al.Pituitary adenoma:possible role of bromocriptine in intratumoral hemorrhage.Radiology,1989,170:239-243.
  • 9Lundin P,Nyman R,Burman P,et al.MRI of pituitary macroadenomas with reference to hormonal activity.Neuroradiology,1992,(34):43-51.
  • 10Asa SL.Practical pituitary pathology:what dose the pathologist need to know? Arch pathol Lab Med,2008,132:1231-1240.

二级参考文献28

共引文献19

同被引文献161

引证文献19

二级引证文献111

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部