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益气活血通络方对老年高血压患者动态血压及T淋巴细胞亚群的影响 被引量:15

The Effect of Decoction of Supplementing Qi and Activating Blood Circulation on 24h Ambulatory Blood Pressure Monitoring and the Level of T-Lymphocyte Sub-population of Old Essential Hypertension Patients
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摘要 目的:观察益气活血通络中药对老年高血压患者动态血压及T淋巴细胞亚群的影响。方法:将60例老年原发性高血压患者随机分为治疗组和对照组,对照组予氨氯地平5mg,治疗组在对照组基础上加用中药益气活血通络方,疗程8周。结果:(1)治疗组对夜间血压下降率的疗效优于对照组,P<0.01。(2)治疗组治疗后血清Th水平较对照组升高,P<0.05。(3)治疗组治疗后中医临床症状积分改善明显,P<0.05。结论:益气活血通络方干预老年高血压患者治疗的作用靶点之一,可能为调整T淋巴细胞亚群的免疫平衡,从而达到有效降压及控制高血压病情发展的作用。 Objective:Observe the effect of decoction of supplementing qi and activating blood circulation on 24h Ambulatory blood pressure monitoring and the Level of T-Lymphocyte Sub-population of old essential hypertension patients( OEH). Methods:The 60 patients were divided into two parts:the treatment group and control group. The control group were offered antihyper-tensive drug Norvasc while the treatment group were offered Norvasc and supplementing qi and activating blood circulation decoction for 8 weeks. Results:( 1) The night-time blood pressure fall rate of treatment group was higher than control group,P 0. 01. ( 2) After the 8 weeks'treatment,the Th level of treatment group was higher than control group,P 0. 05. The ratio of Th/Ts and the Ts level between the two groups has no statistical significance,P 0. 05. ( 3) The symptom integral of both groups ameliorated after the treatment,and the improvement of treatment group was better than the control group,P 0. 05. Conclusion:The results suggested that one of the targets of decoction of supplementing qi and activating blood circulation on the OEH patients may be adjusting the T-Lymphocyte which is one of the function mechanism on decreasing blood pressure and controlling disease development.
作者 李欣 陈咸川
出处 《辽宁中医杂志》 CAS 北大核心 2010年第9期1761-1763,共3页 Liaoning Journal of Traditional Chinese Medicine
关键词 老年高血压 T淋巴细胞 中药 Old Essential Hypertension T-Lymphocyte Sub-population Traditional Chinese Medicine
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