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柴胡疏肝散辨证加减治疗非酒精性脂肪肝54例疗效观察 被引量:9

Clinical investigation of Chaihushugansan on nonalcoholic fatty liver
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摘要 目的观察柴胡疏肝散辨证加减治疗非酒精性脂肪肝的临床疗效。方法将108例非酒精性脂肪肝患者随机分为2组,治疗组54例予柴胡疏肝散辨证加减治疗,对照组54例予西药非诺贝特缓释胶囊治疗。2组疗程均为3个月。观察2组临床疗效、治疗前后肝脏B超积分及血脂变化。结果 2组治愈率、总有效率比较差异均有统计学意义(P<0.05),治疗组临床疗效优于对照组。治疗组治疗后肝脏B超积分较对照组低(P<0.05)。治疗组治疗后血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)较本组治疗前均降低(P<0.05),高密度脂蛋白胆固醇(HDL-C)升高(P<0.05)。治疗组治疗后TC、TG、LDL-C均低于对照组(P<0.05),HDL-C高于对照组(P<0.05)。结论柴胡疏肝散辨证加减治疗非酒精性脂肪肝疗效优于单纯西药治疗。 Objective To investigate the effect of Chaihushugansan on nonalcoholic fatty liver.Methods 108 patients with nonalcoholic fatty liver were randomly divided into two groups. 54 cases in treatment group were treated by differential treatment of Chaihushugansan. Patients in control group (n=54) were treated by fenofibrate sustained release capsules. The course was three months in two groups. The effect, ultrasonic score and changes of blood lipid were observed.Results The total effective rate and cure rate in treatment group were superior to those in control group (P0.05). Ultrasound score of liver in treatment group was decreased compared with that in control group (P0.05). TC, TG and LDL-C in treatment group was decreased compared with that in control group, HDL-C was increased (P0.05). Conclusion The effect of Chaihushugansan was superior to that of routine therapy.
出处 《河北中医》 2010年第8期1129-1131,共3页 Hebei Journal of Traditional Chinese Medicine
关键词 脂肪肝 中药疗法 Fatty liver Traditional Chinese medicine therapy
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