摘要
目的通过研究不同配伍条件下药液中钙离子溶出量变化,探讨白虎汤的配伍规律。方法采用EDTA直接滴定法测定白虎汤中各单味药物、不同配伍条件下和不同浸泡和煎煮时间药液中钙离子含量。结果原方各单味均含钙,其中石膏含钙量最高,其次为知母和甘草,粳米含钙量最低。当石膏与其它药物配伍合煎后,药液中钙离子溶出量除石膏与甘草配伍略微增高外,其余各组均降低。石膏和复方药液中钙离子溶出量随浸泡时间延长而增加,随煎煮时间增加而降低。但复方药液中钙离子溶出量随煎煮时间延长而降低的较为缓慢,单味石膏钙离子溶出量下降迅速。结论除石膏与甘草配伍增加其钙离子溶出量外,石膏与其它各药配伍均降低其钙离子溶出量。增加浸泡时间可使石膏中钙离子溶出量增高,增加煎煮时间使药液中钙离子溶出量降低。
Objective To study the content of calcium ion solubility with different compatibility and to explore the compatible regularity of Baihu Decoction.MethodsThe direct titration was used to study the content of soluble calcium ion of each single herb of Baihu Decoction,their different compatibility,different soaking and boiling time of decoction.ResultsAll of herbs in Baihu Decoction contain calcium.Gypsum had the highest content of calcium,followed by Rhizoma Anemarrhenae and Licoroce,Rice had the lowest.When gypsum compatible with other herbs,the calcium ion content of decoction all descend except gypsum and Licorice compatibility group were slightly increased.The calcium ion solubility of gypsum and Baihu Decoction all increased with extend time of soak.But the solubility of calcium ion decreased with boiling time,especially the group of gypsum declined rapidly.ConclusionExcept the content of calcium ion solubility with gypsum and Licoroce group slightly increase,the other compatibility group content of calcium ion solubility all decreased.The content of calcium ion solubility will enable increased with extending the soaking times,and decreased with extending boiling time.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2010年第9期2178-2179,共2页
Lishizhen Medicine and Materia Medica Research
基金
内蒙古自治区高等学校自然科学研究重点项目(No.NJ09157)
内蒙古自治区高等教育科学"十一五"规划课题(No.NGJGH08131)
内蒙古自然科学基金项目(No.200711020913)
关键词
白虎汤
钙离子含量
石膏
配伍
Baihu Decoction
Content of calcium ion
Gypsum
Compatibility
