摘要
采用放射免疫方法检测１０２例各型病毒性肝炎血清Ⅳ型胶原（ⅣＣ）、层粘连蛋白（ＬＮ）的变化，并与Ｂ型超声仪检测的门静脉主干管径比较。结果发现：在慢性重度肝炎及重症肝炎血清ⅣＣ，ＬＮ水平升高，在门静脉管径＞１２ｍｍ时，其血清ⅣＣ，ＬＮ值明显上升，且与门静脉管径呈正相关。表明血清ⅣＣ，ＬＮ的检测对肝纤维化的诊断有重要参考价值。
The contents of serum Type Ⅳ collagen and laminin were detected by radioimmunoassay and the diameters of portal veins were measured by B mode ultrasound in 102 patients with different type of viral hepatitis. The results show that an increase of levels of Type Ⅳ collagen and laminin was found in patiens with chronic severe hepatitis and fulminant hepatitis. The levels of Type Ⅳ collagen and laminin were obviously increased in the patients who have the diameter of portal vein≥12mm compared with the patients who have the diameter of protal<12mm. There was a positive correlation between the levels of Type Ⅳ collagen, laminin and the diameters of portal vein.
出处
《湖南医科大学学报》
CSCD
1999年第3期277-278,281,共3页
Bulletin of Hunan Medical University
关键词
肝炎
病毒性肝炎
层粘连蛋白
Ⅳ型胶原
门静脉
hepatitis
viral
human
Type Ⅳ collagen *
laminin
width of portal vein *
