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一氧化氮与抑郁症发生的相关性 被引量：10

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摘要 抑郁症是近年来发病率较高的精神疾病,给社会造成重大负担,其发病机制逐渐受到广泛的关注和研究。大量的基础及临床研究均证明一氧化氮可能参与抑郁症的发病过程,包括抑郁症患者血清及脑内一氧化氮升高,一氧化氮合酶及NMDA受体拮抗剂对抑郁症治疗有效等,这些研究提出了抑郁症发病机制的新观点,为临床治疗抑郁症提供了新的理论依据。
作者 李欣 周虹 杨宝学
机构地区 北京大学医学部基础医学院药理学系
出处 《国际神经病学神经外科学杂志》 2010年第4期352-356,共5页 Journal of International Neurology and Neurosurgery
基金 国家自然科学基金(30870921) 国家985计划(985-2-094-121)
关键词 抑郁症 一氧化氮 一氧化氮合酶
分类号 R749.4 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献34

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二级参考文献32

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共引文献14

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引证文献10

二级引证文献110

国际神经病学神经外科学杂志
2010年 第4期

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