摘要
目的:探讨纳米材料的组织工程学特性及其修复运动性韧带损伤的性能评价。方法:以"韧带损伤;纳米材料;修复;组织工程;生物力学"为中文关键词;以:"cruciateligament;nanomaterials;tissue engineering;application;ligamentre construction"为英文关键词,采用计算机检索中国期刊全文数据库(1993-01/2010-04)、PubMed数据库(1993-01/2010-04)相关文章。纳入与纳米材料修复运动性韧带损伤相关的文章;排除重复研究或Meta分析类文章。结果:共纳入相关文献16篇。临床常用的纳米材料有无机纳米材料、高分子有机材料、纳米复合材料及仿生纳米材料。各类纳米材料的组织工程学共性为:①尺寸在纳米量级。②有大量的界面或自由表面。③各纳米单元之间存在着或强或弱的相互作用。从临床应用效果来看,纳米材料可有效修复韧带的损伤。结论:纳米材料在运动性韧带损伤的修复治疗中性能良好,是最具应用潜力的生物材料之一。
OBJECTIVE：To explore the tissue engineering characteristics of nano-materials,and to evaluate the repair effect of exercise ligament injury.METHODS：Using ＂ligament injury;nano-materials;repair;tissue engineering;biomechanics＂ as the Chinese ;＂cruciate ligament;nanomaterials;tissue engineering;application;ligament reconstruction＂ as the English key words,a computer search was performed on China Academic Journal database and PubMed database from January 1993 to April 2010.Articles of nano-materials to repair exercise ligament injury were included;repeated study or Meta analysis articles were excluded. RESULTS：A total of 13 relevant literatures were included.The nano-materials commonly used in clinics are inorganic nano-materials,polymer organic materials,nano-composite materials and biomimetic nano-materials.Tissue engineering characteristics of various types of nano-materials are as follows：① nanometer-scale size;② numerous interfaces or free surfaces.③ strong or weak interactions between the nano-units.From the clinical application point of view,nano-materials can be used to repair ligament injury.CONCLUSION：The nano-materials perform well in the repair treatment of exercise ligament injury,and it is one of the most potential biological materials.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2010年第34期6449-6452,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
