摘要
目的探讨非诺贝特致药品不良反应(ADRs)的一般规律和特点。方法检索PubMed(1978年-2009年8月)、中国期刊全文数据库CNKI(1980年-2009年8月)、中国生物医学文献数据库CBMDise(1980年-2009年8月)非诺贝特所致ADRs文献,进行统计、分析。结果非诺贝特致ADRs多发生在>40岁年龄段,与性别无显著关联;64例ADRs主要涉及骨骼肌肉系统、消化系统、泌尿生殖系统、过敏反应,及时处理者预后良好。结论临床上应重视非诺贝特所致ADRs,及时处理。
Objective To analyse the clinical features,correlation factors,preventions and cures of （ adverse drug reactions,ADRs） caused by fenofibrate. Methods The cases of ADRs caused by fenofibrate were collected and analyzed from Pubmed （ 1978 -August 2009） ,CNKI （ 1980 -August 2009） and CBMDise （ 1980 -August 2009）. Results Fenofibrate-induced ADRs were mostly seen in patients over 40 years old,but which was independent for sex. Totally,64 ADRs were involved in the skeletal musculature system,digestive system,urinogenital system,and allergic response. The prognosis was favorable. Conclusion More attention should be given to patients with fenofibrate and ADRs should be treated as soon as possibile.
出处
《华西医学》
CAS
2010年第8期1536-1538,共3页
West China Medical Journal
关键词
非诺贝特
不良反应
文献分析
Fenofibrate
Adverse drug reactions
Literature analysis
