摘要
目的:了解医院住院病人肺炎相关病原菌的耐药情况。方法:选取荆州市第一人民医院检验科2010年上半年标本培养结果中可能引起肺炎的相关菌种,并进行耐药性检测。结果:共检出肺炎相关病原菌687株,其中革兰阴性菌317株,革兰阳性菌370株。药敏结果显示产EBSLs的肺炎克雷伯菌与大肠埃希菌、粪肠球菌对三、四代头孢类抗生素有较高的耐药率。"抗生素+酶抑制剂"能有效降低细菌的耐药性。结论:在治疗肺炎相关细菌引起的感染时,头孢菌素仍是首选,但产酶(EBSLs)菌属应使用"抗生素+酶抑制剂"药物或泰能治疗。
Objective:To understand the antibiotic resistance of pneumonia pathogenic bacteria in hospital in-patient department.Methods:Tests of antibiotic resistance of pneumonia-related bacteria,during the first half of 2010,department of microbiology,No.1 People's Hospital of Jingzhou City.Results:There are 687 pneumonia-related pathogens,including 317 gram-negative bacteria,370 Gram-positive bacteria.EBSLs in Klebsiella pneumoniae and Escherichia,Enterococcus faecalis have a high resistance rate in the third-generation and fourth-generation cephalosporin.The method 'antibiotics + enzyme inhibitor' can effectively reduce the rate of antibiotic resistance.Conclusion:The cephalosporin is effective in treating infections caused by pneumonia-related bacteria.The method 'antibiotics + enzyme inhibitor ' is good for EBSLs-caused infection.
关键词
肺炎
病原菌
耐药性
Pneumonia
Pathogens
Antibiotic resistance
