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乳胶增强免疫比浊测定血清胃蛋白酶原及其在胃癌诊断中的应用 被引量:4

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摘要 目的分别测定正常人和胃癌及胃癌患者手术前后血清胃蛋白酶原Ⅰ(PGⅠ)、PGⅡ及PGⅠ/PGⅡ(PGR),以了解对胃癌诊断的临床价值。方法用乳胶增强免疫比浊法检测60例健康人,70例胃溃疡患者,52例胃癌手术前患者血清胃蛋白酶原的含量。结果胃溃疡患者与对照组相比血清PG含量无显著性变化;而胃癌患者与对照相比血清PGⅠ显著性下降(t=6.74,P<0.01),PGⅡ差异无显著性(t=0.209,P>0.05),PGR显著性下降(t=3.036,P<0.01)。胃癌患者手术后与术前比较PGⅠ显著性下降(t=14.61,P<0.01),PGⅡ显著性下降(t=8.15,P<0.01),PGR无显著性差异(t=0.81,P>0.05)。结论血清PGⅠ、PGⅡ及PGR对胃癌的诊断及预后判断具有重要的临床意义。
出处 《临床检验杂志》 CAS CSCD 北大核心 2010年第5期338-339,共2页 Chinese Journal of Clinical Laboratory Science
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