期刊文献+

减肥治疗前后胰岛素抵抗的变化 被引量:1

The changes of insulin resistance before and after weight loss treatment
原文传递
导出
摘要 目的研究单纯性肥胖患者短期内体质量剧烈波动导致的胰岛素抵抗变化。方法采用前瞻性自身对照研究。研究对象为94例女性单纯肥胖患者,BMI〉128kg/m^2。予低热量低碳水化合物低脂高蛋白饮食+拔罐或针灸治疗2个月,在基线、2个月、6个月和12个月测量体质量、BMI、腰围、臀围、血糖、血胰岛素,评价胰岛素抵抗情况。结果经减肥治疗2个月,83例患者体质量、BMI、腰围、臀围、空腹胰岛素、HOMA—IR指数均显著下降(P〈0.01或P〈0.05)。6个月随访时,这些指标有反弹趋势。12个月时体质量、BMI、腰围、臀围恢复至基线水平;其中44%患者体质量反弹,空腹胰岛素水平、HOMA-IR指数显著性升高(P〈0.05)。结论低热量低碳水化合物低脂高蛋白饮食+拔罐或针灸治疗可以有效治疗肥胖,但12月随访时部分患者体质量反弹,并且导致追赶生长和胰岛素抵抗情况加重。 Objective To study the changes of insulin resistance due to severe short-term fluctuations of body mass in simple obese patients. Methods 94 women with simple obesity, were treated by low caloric and high protein diet for two months. A series of examinations were taken before and after the treatment. Results After two months ,weight ,body mass index (BMI), waist, hip, fasting serum insulin and HOMA-IR reduced significantly (P 〈 0. 01 or P 〈0. 05). But after 6 months follow-up,these data began to regain. After 12 months,these data were not significantly different. Fasting serum insulin and HOMA-IR increased ( P 〈 0. 05 ). Conclusions The low caloric and high protein diet combined acupuncture or cupping could reduce weight. But 44% patients weight rebound, and HOMA-IR increased.
出处 《中国基层医药》 CAS 2010年第18期2474-2475,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 肥胖症 体重变化 热量限制 胰岛素抵抗 Obesity Body weight changes Caloric restriction Insulin resistance
  • 相关文献

参考文献4

二级参考文献21

  • 1刘志诚,张京英,肖少卿,胡丽梅,钱真良,汤元成,顾兆军,邱莉,王沂争,周群,施小波.针灸对单纯性肥胖病人植物神经外周介质的影响[J].针灸学报,1989(1):15-19. 被引量:37
  • 2孙凤岷,刘志诚,王沂争,李嘉,胡葵.针灸减肥及其对水盐代谢的影响[J].针刺研究,1996,21(2):19-24. 被引量:31
  • 3Yoon KH, Lee JH, Kim JW, et al. Epidemic obesity and type 2 diabetes in Asia. Lancet, 2006,368 : 1681-1688.
  • 4Meszaros K, Lang CH, Bagby GJ, et al. Contribution of different orgalls to increased glucose consumption after endotoxin administration. J Biol Chem, 1987,15,262 : 10965-10970.
  • 5Huisamen B, van Zyl M, Keyser A, et al. The effects of insulin and bcta-adrencrgic stimulation on glucose transport, glut 4 and PKB activation in the myocardium of lean and obese non-insulin dependent diabetes mcllitus rats. Mol Cell Biochem,2001,223 :15-25.
  • 6Buchan IE, Heller RF, Clayton P, et al. Early life risk factors for obesity in childhood : early feeding is crucial target for preventing obesity in children. BMJ,2005 ,331:453-454.
  • 7Soto N, Bazaes RA, Pena V, et al. Insulin sensitivity and secretion are related to catch-up growth in small-for-gestational-age infants at age 1 year: results from a prospective cohort. J Clin Endocrinol Metab,2003, 88:3645-3650.
  • 8Carbonnel F, Messing B, Rimbert A, et al. Energy and protein metabolism during recovery from malnutrition due to nonneoplastic gastrointestinal disease. Am J Clin Nutr,1997 ,65 :1517.
  • 9Debray C, Zarakovitch M, Ranson B, et al. Contribution to the study on the pathology of the deportees. Seminaire Hospital de Paris, 1946, 22 : 863 -870.
  • 10Barac-Nieto M, Spurr GB, Lotero H, et al. Body composition during nutritional repletion of severely undernourished men. Am J Clin Nutr, 1979,32:981-991.

共引文献26

同被引文献2

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部