摘要
目的:探讨尼麦角林与奥拉西坦联合治疗血管性认知障碍的疗效。方法:选取血管性认知功能障碍患者90例随机分为3组各30例,尼麦角林组给予尼麦角林治疗,奥拉西坦组给予奥拉西坦治疗,联合治疗组则采用两种药物同时服用,疗程均为12周。以精神状态检查表、韦克斯勒记忆量表、日常生活能力量表为评价指标,评价3组疗效。结果:实际评估86例,3组治疗前后差异均有显著性(P<0.05),无明显不良反应,且联合治疗组优于其他两组。结论:尼麦角林联合奥拉西坦能明显改善患者的认知功能障碍。
Objective：To study the therapeutic effect of nicergoline and oxiracetam treatment patients with vascular cognitive impairment. Method： ninety subjects were divided into three groups randomly nicergoline group ,oxiracetam group combined treatment group, treatment course wasl 2weeks. MMSE, WMS, ADL were used assessing items. Result： A realistic assessment of 86 patients,3 patients before and after treatment were significantiy, no significant adverse reactions, and the combined treatment group than other two groups. Conclusion： Nicergoline combined with oxiracetam should be good choice improving cognitive function vascular cognitive impairment patients.
关键词
尼麦角林
奥拉西坦
血管性
认知障碍
nicergoline
oxiracetam
vascular cognitive impairment
