摘要
目的探讨血浆置换(PE)联合血液透析滤过(HDF)治疗重型肝炎的临床效果。方法将119例重型肝炎患者随机分为A、B、C三组,均在内科治疗的基础上,A组47例接受PE治疗,B组32例接受PE+HDF治疗,C组不接受人工肝治疗。结果 A组治愈16例,好转22例,死亡9例,B组治愈9例,好转17例,死亡6例,C组治愈7例,好转22例,死亡11例;PE或PE+HDF治疗后,患者血NO、LPS、TNF-α下降明显。结论 PE或PE联合HDF治疗重型肝炎,能显著改善临床症状、促进肝性脑病恢复,提高患者存活率。
Objective To investigate plasma exchange（PE）and hemodiafiltration（HDF）treatment in patients with fulminant hepatitis.Methods 119 patients with severe hepatitis were randomly divided into three groups.The basic medical treatment was the same.47 cases in group A received PE,32 in group B received with PE＋HDF.Results In group A,16 patients recovered,22 improved and 9 died,in group B,9 recovered,17 improved,and 6 died,and in group C,7 recovered,22 improved and 11 died;NO,LPS,TNF alpha dropped significantly after the treatment of liver supporting.Conclusion PE and HDF treatment in patients with fulminant hepatitis can significantly decrease TBIL,NH3,NO LPS,TNF alpha,and improve the survival rate of the patients.
出处
《实用肝脏病杂志》
CAS
2010年第5期352-353,共2页
Journal of Practical Hepatology
关键词
重型肝炎
血浆置换
血液透析滤过
Severe hepatitis
Plasma exchange
Hemodiafiltration
