摘要
目的分析库肯勃瘤的临床特点和相关预后因素。方法对2000~2009年10年间我院收治的11例库肯勃瘤的临床资料进行回顾性分析。采用单因素统计方法分析不同病理类型及手术方式、疾病诊断间隔时间及化疗等对库肯勃瘤预后的影响。结果印戒细胞癌患者存活时间较非印戒细胞癌短。细胞角蛋白7（CK7）、P53基因表达阳性的卵巢转移癌患者的生存时间短于阴性者。施行瘤体减灭术的患者存活时间相对于其他手术长。化疗与否对生存时间的影响无显著差异。结论对库肯勃瘤早诊断、早治疗,尽可能行瘤体减灭术是提高库肯勃瘤预后的关键。
Objective To evaluate the clinical characteristics and prognosis of Krukenberg tumor.Methods Eleven cases of Krukenberg tumor treated in our hospital from 2000 to 2009 were retrospectively reviewed.Univariate analysis was used to identify two pathologic patterns and different surgeries associated with the survival and prognosis of patients.Results Signet-ring cell carcinoma exhibited a worser prognosis.Patients with CK7＋ and P53 gene expression positive ovarian cancer metastasis had shorter survival time than the negative.Patients underwent tumor reductive surgeries had a better survival than others.Chemotherapy showed no significant increase on survival time.Conclusion In order to improve the survival of Krukenberg tumor,early diagnosis,early treatment and undergoing tumor reductive surgery are necessary.
出处
《临床和实验医学杂志》
2010年第19期1453-1454,共2页
Journal of Clinical and Experimental Medicine
关键词
库肯勃瘤
印戒细胞癌
手术治疗
预后
Krukenberg tumor
Signet-ring cell carcinoma
Operative therapy
Prognosis
