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精浆免疫抑制物(SPIM)活性低下与反复自然流产关系及中药治疗的研究 被引量:2

Interrelative studies between recurrent spontaneous abortion and activated decrease of SPIM along with it's traditional Chinese medical therapy.
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摘要 1对正常生育组84对及反复自然流产组的186对夫妇进行了研究。用抗补体法对丈夫精浆测定SPIM活性,结果表明:反复自然流产组SPIM活性3892±615×103u/L低于正常生育组4386±664×103u/L,差异显著(P<0.01)。说明SPIM活性低下是反复自然流产的原因之一。2用“升抑汤”对75例SPIM活性低下的患者作1-3个疗程的治疗,SPIM活性由3482±521×103u/L上升到4263±618×103u/L,治疗前后差异显著(P<0.01)。治疗后与正常生育组相比差异无显著性,这说明“升抑汤”是治疗SPIM活性低下的有效方剂。 Using anticomplement method to measure the activity of seminal plasma immnological materials (SPIM) of husbands seminal plasma (SP),We have studied these two groups 84 normal couples versus 186 couples affected by recurrent spontaneous abortion (RSA).The results indicated that the average SPIM activated values of RSA groups was 389.2±61.5×10 3U/L and was lower than that of normal groups which was 438.6±66.4×10 3U/L.By comparison,here was significant difference between them.That showed that activated decrease of SPIM was the main cause of RSA. 2.One to three therapy courses were also preaented to 75 individuals affected with SPIM activated decrease,using 'Shengyitang'.We found that their averageactivity of SPIM was increased from 348.2±52.1×10 3U/L to 426.3±61.8×10 3U/L.The significant difference existed by comparing protherapy to posttherapy while there was no significant difference between posttherapy group and no mal group.The outcome showed that 'Shengyitang' offered the best hope for treating activated decrease of SPIM.
作者 王永征 李霞
出处 《中国优生与遗传杂志》 1999年第3期75-75,91,共2页 Chinese Journal of Birth Health & Heredity
关键词 精浆免疫抑制剂 自然流产 中医药疗法 Seminal plasman immunological materials (SPIM),Recurrent spontaneous abortion (RSA),Traditional Chinese Medical therapy. (Original article on page 75)
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  • 1李大金,李超荆,朱影.不育的免疫性因素分析研究[J].中国免疫学杂志,1995,11(4):232-234. 被引量:17
  • 2金之刚 陈文伯.男性不育与性功能障碍(第1版)[M].学苑出版社,1991.104,308.
  • 3黄宇烽.不孕症的免疫学检查和临床应用[J].解放军医学杂志,1988,13:456-456.
  • 4闫乐法 王永征 高细军 等.调免汤对提高精浆免疫抑制物活性的疗效观察[J].中国医药学报,1993,8(5):53-53.

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