摘要
目的 探讨干预口腔内微环境与ICU呼吸机相关性肺炎（VAP）的关系.方法 将217例经口气管插管的机械通气患者随机分为A、B、C三组.A组采用生理盐水作为口腔护理液（1次/d）;B组和C组均采用碳酸氢钠与过氧化氢的混合液作为口腔护理液,B组口腔护理1次/d,C组口腔护理1次/4h.观察三组患者口腔pH值、口腔分泌物菌落计数、口腔异味、口腔溃疡及呼吸机相关性肺炎发病率的变化.同时设正常对照组（D组）.结果 C组采用碳酸氢钠与过氧化氢的混合液作为口腔护理液（口腔护理1次/4 h）,较其他两组口腔pH值升高（P〈0.05）,口腔分泌物菌落计数、口腔异味、口腔溃疡及VAP发病率下降（P〈0.05）.结论 干预口腔内微环境,能在一定程度上预防VAP的发生.
Objective To explore the relationship between ventilator - associated pneumonia and the intervention of oral micro - environment. Methods The 217 cases of mechanical ventilation with tracheal cannula was randomly divided into 3 groups ： A group （ oral care with NS, qd）, B group （oral care with sodium bicarbonate and hydrogen peroxide, qd）, C group （oral care with sodium bicarbonate and hydrogen peroxide, q 4 h）. pH, oral secretions colony - count, oral odor, oral ulcers and the incidence of ventilator - associated pneumonia of three groups patients were observed; D group （ the normal control group） at the same time. Results pH of C group was higher than that of other two groups （P 〈 O. 05 ）; oral secretions colony- count, oral odor, oral ulcers and the incidence of ventilator - associated pneumonia were lower than those of other two groups （ P 〈 O. 05 ）. Conehtsion Intervention of oral micro - environments prevent ventilator - associated pneumonia to a certain extent.
出处
《中国急救医学》
CAS
CSCD
北大核心
2010年第9期826-828,共3页
Chinese Journal of Critical Care Medicine
