摘要
目的:探讨大肠癌患者舌苔脱落细胞EGFR表达与舌苔变化的关系。方法:HE染色及SP法观察46例患者舌苔脱落细胞EGFR表达。结果:厚苔组、薄苔组及花剥少苔组之间差异均有统计学意义,F值分别为31.78(细胞直径)、54.31(着色程度),P均<0.05。厚苔组舌苔脱落细胞EGFR的表达(细胞直径:54.14±1.47;着色程度:2.02±0.18)最强。黄苔组与白苔组差异均有统计学意义,F值分别为5.06(细胞直径)、5.58(着色程度),P均<0.05。黄苔组舌苔脱落细胞EGFR的表达(细胞直径:53.74±1.97,着色程度:1.93±0.36)比白苔组强。结论:大肠癌患者舌苔脱落细胞EGFR表达与舌苔变化有明显的相关性。
OBJECTIVE：To investigate the relationship between the change of tongue demonstration and expression of EGFR in the cast-of cell of furred tongue in colorectal cancer patients. METHODS：The cast-of cell was observed by hematoxylin-eosin staining （HE staining） and EGFR immunohistochemical staining. RESULTS：There were significant differences among the thick-fur group,the thin-fur group and the exfoliative-fur group. The F values were 31.78 （cell diameter）,54.31 （color degree）,and all P0.05. The expression of EGFR in the thick-fur group （cell diameter：54.14±1.47,color degree：2.02±0.18） was the strongest among the three groups. There were significant differences between the yellowish-fur group and the whitish-fur group. The F values were 5.06 （cell diameter） and 5.58 （color degree）,and all P0.05. The expression of EGFR in yellowish-fur group （cell diameter：53.74±1.97,color degree：1.93±0.36） was stronger than that in the whitish-fur group. CONCLUSTION：There is significant correlation between tongue fur and expression of EGFR in the cast-of cell of furred tongue in colorectal cancer patients.
出处
《中华肿瘤防治杂志》
CAS
2010年第17期1348-1350,共3页
Chinese Journal of Cancer Prevention and Treatment
基金
广东省中医药局科研项目(2007102)
关键词
结直肠肿瘤
舌苔
受体
表皮生长因子受体
colorectal neoplasms
TONGUE COATING
receptor
epithelial growth factor
