摘要
目的:了解碘特需人群碘营养状况,为科学补碘提供依据。方法:随机抽样,B超法检查甲状腺,砷铈催化分光光度法测定尿碘浓度,化学发光法检测甲状腺激素,直接滴定法检测盐碘含量,三日秤量法计算食盐消耗量。结果:调查8～10岁儿童62人,甲状腺肿大率19.35%,孕妇30人,检出甲状腺结节4人,检出率13.33%,哺乳期妇女30人,检出桥本甲状腺炎4人、结节2人,检出率20.00%,18～45岁成人25人,查出桥本甲状腺炎1人、结节4人,检出率20.00%,儿童甲状腺结节和甲状腺炎患病率显著低于孕妇(χ2=5.7659P<0.05)、哺乳期妇女(χ2=10.1587P<0.01)和成人(χ2=9.6903P<0.01),差别均有统计学意义。儿童、孕妇、哺乳妇女和成人尿碘中位数(MUI)分别为180.74μg/L、95.60μg/L、128.88μg/L和139.84μg/L,儿童尿碘均值高于成人、哺乳期妇女和孕妇(t=2.3595,P<0.05;t=2.7739,P<0.01;t=4.8221,P<0.01),成人与哺乳期妇女和孕妇比较(t=0.4017,t=1.7387,P>0.05),哺乳期妇女与孕妇比较(t=1.3698,P>0.05),差别均无统计学意义;TSH异常10人(减低5人,升高5人),异常率6.80%,TgAb和TPOAb阳性14人,阳性率9.52%。人日均食盐消耗量8.24 g,碘摄入量258.98(187.38～330.59)μg/d;6份饮用水水碘含量2.45μg/L～5.74μg/L。结论:当地自然环境缺碘,儿童甲状腺肿大率偏高,人群碘消耗量基本符合WHO推荐供应量,儿童、哺乳妇女和成人碘营养状态适宜,孕妇轻度碘缺乏。
Objective：About special needs iodine nutrition status,provide the basis for scientific iodine.Methods： Random sampling,use B-type-ultrasonic-scanning-method to check the thyroid.Catalytic Spectrophotometric Determination of arsenic and cerium concentration of urinary iodine.Chemiluminescence detection of thyroid hormone.Direct Titration of salt iodine content.Three-day weighing method of salt consumption.Results： Survey of children aged 8 to 10,62,19.35% goiter rate,30 pregnant women,and the detection of thyroid nodules 4,the detection rate of 13.33%,30 lactating women,and the detection 4 Hashimoto thyroiditis,nodular 2,the detection rate of 20.00%.Adults aged 18 to 45 of 25 people found 1 Hashimoto′s thyroiditis,nodular 4,the detection.Children thyroid disease were significantly lower than pregnant women（χ2=5.7659,P0.05）,breast-feeding women（χ2=10.1587 P0.01） and adults（χ2=9.6903 P0.01）,differences were statistically significant.Children,pregnant women,lactating women and adult median urinary iodine（MUI）, respectively 180.74 μg/L,95.60 μg/L,128.88 μg/L and 139.84 μg/L.Mean urinary iodine than adults,lactating women and pregnant women （t=2.3595,P0.05;t=2.7739,P0.01;t=4.8221,P0.01）,Adults and pregnant women,lactating women and compared（t=0.4017,t=1.7387,P0.05）,breast-feeding women and pregnant women compared（t=1.3698,P0.05）.There was no significant difference.Abnormal TSH 10（reduced by 5 people,increase of 5）,abnormal rate of 6.80%,TgAb and TPOAb-positive and 14,the positive rate of 9.52%.People daily salt consumption 8.24 g,iodine intake 258.98 （187.38～330.59）μg/d;6 copies of drinking water iodine content of 2.45 μg/L～5.74 μg/L.Conclusion： The local natural environment of iodine deficiency,High goiter rate of children.iodine consumption,the basic line with WHO recommended supply.Children,lactating women and adult nutritional status of iodine appropriate. Pregnant women with mild iodine deficiency.
出处
《中国卫生检验杂志》
CAS
2010年第10期2576-2578,共3页
Chinese Journal of Health Laboratory Technology
关键词
碘
摄入量
甲状腺
尿碘
儿童
孕妇
哺乳期妇女
成人
Iodine
Intake
Thyroid
Urinary iodine
Children
pregnant women
lactating women
adults
