摘要
目的:分析鲍温样丘疹病(BP)的临床特点,提高诊治水平。方法:回顾性分析42例鲍温样丘疹病患者的临床表现、组织病理、人乳头状瘤病毒(HPV)检测情况,比较5-氟尿嘧啶软膏涂敷、激光照射和干扰素-α2b注射液治疗BP疗效。结果:鲍温样丘疹病多发生在年轻人,HPV16DNA阳性率达64.2%,被误诊尖锐湿疣和鲍温病的误诊率达88.68%,均在2～13周治愈,随访6～12个月未见复发。结论:HPV与BP发生、发展关系密切,要注意与尖锐湿疣和鲍温病的鉴别,以防误诊,干扰素-α2b治疗BP见效更快,复发率低。
Objective：To analyse the clinical features of Bowenoid papulosis（BP）,and to improve the diagnosis and treatment.Methods：We retrospectively analysed clinical manifestations,pathology,human papilloma virus（HPV）testing of 42 Bowenoid papulosis patients,and compared the effects of 5-fluorouracil ointment coating,laser irradiation and interferon-α 2b injection for BP.Results：Bowenoid papulosis mostly occurred in the young;HPV16DNA positive rate was 64.2%;the misdiagnosis rate of Bowen＇s disease and condyloma was 88.68%,who were cured in 2 to 13 weeks,no recurrence was found during followed up for 6 to 12 months.Conclusions：HPV and has close relations with occurrence and development of BP.We should pay attention to the identification of patients with Bowen＇s disease and condyloma.Interferon-α 2b can treat BP effectively,with lower recurrence rate.
出处
《现代生物医学进展》
CAS
2010年第18期3510-3512,共3页
Progress in Modern Biomedicine
关键词
鲍温样丘疹病
临床特点
组织病理
疗效
鉴别诊断
Bowenoid papulosis clinical features pathology effect differential diagnosis
