摘要
目的探讨急性脑梗死(ACI)患者的血清脂联素、超敏C-反应蛋白(hs-CRP)、血脂变化,分析其相关性。方法检测64例ACI患者(ACI组)、20例健康体检者(对照组)的血清脂联素、hs-CRP及血脂,并对三者进行相关性分析。结果与对照组比较,ACI组血清脂联素、HDL-C降低,hs-CRP、TG升高(P均<0.01)。相关分析显示,脂联素水平与hs-CRP、LDL-C呈负相关(r分别为-0.358、-0.281,P<0.01或<0.05),与HDL-C呈正相关(r=0.286,P<0.05);hs-CRP与LDL-C呈正相关(r=0.356,P<0.01)。结论 ACI患者血清脂联素降低、hs-CRP升高、血脂异常,三者相互影响,在ACI发生、发展中起重要作用。
Objective To observe the serum level of adiponectin,high sensitive C-reactive protein（hs-CRP） and blood-fat in patients with acute cerebral infarction（ACI）,and analyzed their correlation.Methods Serum concentration of adiponectin,hs-CRP and blood-fat were measured in 64 patients with ACI（ACI group） and 20 healthy subjects（control group）,and correlation analysis was done between them.Result When compared to control group,serum concentration of adiponectin and HDL-C decreased,hs-CRP and TG decreased in ACI group（all P0.01）.Correlation analysis showed that serum concentration of adiponectin were negatively correlated with hs-CRP and LDL-C（r=-0.358,P0.01;r=0.281,P0.05）,while positively correlated with HDL-C（r=0.286,P0.05）.hs-CRP was positively correlated with LDL-C（r=0.356,P0.01）.Conclusion In patients with ACI,the serum levels of adiponectin were decreased,hs-CRP increased,blood fat disorderd.Adiponectin,hs-CRP and blood-fat may influence each other and play an important role in the occurrence and development of ACI.
出处
《山东医药》
CAS
北大核心
2010年第37期12-13,共2页
Shandong Medical Journal
基金
广西壮族自治区科技厅科学研究与技术开发计划项目(桂科攻0719006-2-9)
关键词
脑梗死
急性
脂联素
超敏C-反应蛋白
血脂
cerebral infarction acute
adiponectin
C-reactive protein
high sensitivity
blood-fat
