摘要
目的观察白芍总苷联合柳氮磺胺吡啶治疗强直性脊柱炎的疗效和安全性。方法 42例符合强直性脊柱炎的标准的患者随机分为治疗组22例和对照组20例,治疗组口服白芍总苷和柳氮磺胺吡啶,对照组口服柳氮磺胺吡啶,两组均给予消炎止痛药物,疗程为6个月。结果经过6个月的治疗,两组间的晨僵持续时间、血沉、C反应蛋白、胸廓扩张度、Schober实验等指标方面较治疗前均明显降低,两组之间的晨僵持续时间、血沉、C反应蛋白的差别具有显著意义。治疗组不良反应的发生率明显小于对照组。结论白芍总苷联合柳氮磺胺吡啶治疗AS具有疗效确切不良反应小等优点,在临床有推广意义。
Objective To observe the effect and safety of totalglycosidesofpaeony combined with sulfasalazine in treatment of ankylosing spondylitis.Methods 42patients with ankylosing spondylitis were divided into therapy group（n=22）and control group（n=20）,therapy group received totalglycosidesofpaeony and sulfasalazine,and control group received sulfasalazine,and two groups received antiphlogistic anodyne drug.The course of treatment was 6 months.Results The morning stiffness duration、ESR、C-reaction protein、thoracic expansion and Schober test,etc in two groups were all obvious decrease after therapy than before therapy.The difference of morning stiffness duration、 ESR and C-reaction protein had significance between therapy group and control group.The occurring rate of adverse reactions was obvious lower in therapy group than control group.Conclusion The advantages of talglycosidesofpaeony combined with sulfasalazine in treatment of ankylosing spondylitis include approval results and low side effect,etc.
出处
《中国误诊学杂志》
CAS
2010年第29期7064-7065,共2页
Chinese Journal of Misdiagnostics
