摘要
目的了解本院近2y来抗菌药物不良反应(ADR)发生和分布情况,为临床使用抗菌药物提供参考。方法对本院2008～2009年涉及抗菌药物386例ADR利用Excel建立相关表格,分别对报告所涉及的患者性别与年龄、引起ADR药物的种类、名称、给药方式、原患疾病、ADR临床表现等进行回顾性统计和分析。结果在386例ADR报告中静脉滴注给药引起ADR最多;抗菌药物种类及病例数统计中,共涉及10类44个品种;主要不良反应为皮肤及附件损害、神经系统损害、消化系统损害等。结论医疗机构必须加强抗菌药物使用管理,加强抗菌药物不良反应监测,减少或避免ADR发生。
Objective To study the occurrence and distribution of adverse drug reactions（ADR）reduced by antibacterials in our hospitals in two years lately,and to provide reference for clinical antibacterial use.Methods 386 reports of ADR cases induced by antibacterial from 2008 to 2009 in our hospital were collected and analyzed retrospectively by drug types,drug names,route of administration,original diseases and clinical manifestations.Results The most incidences of 386 reports were related to intravenous injections.44 drugs of 10 categories were involved in 386 reports of ADR.The most common ADRs occurred in the skin systems,and followed by central nervous systems and digestive systems.Conclusion To reduce or avoid the occurrence of ADR,the management and the monitor of ADR of antibacterials should be strengthened in medical institutions.
出处
《今日药学》
CAS
2010年第10期43-46,共4页
Pharmacy Today
基金
深圳市罗湖区科学技术局基金资助(编号:2006-8)
关键词
抗菌药物
不良反应
回顾性分析
antibacterial agent
adverse drug reaction
retrospective analysis
