摘要
目的观察羟基喜树碱联合长春地辛及顺铂治疗晚期非小细胞肺癌的疗效。方法将我院晚期非小细胞肺癌的患者分为两种,VP组20例:予长春地辛50mg静脉推注第1天及第8天、顺铂40mg静脉滴注第1天至第3天;VPH组26例:予羟基喜树碱10mg静脉滴注第1天至第5天。长春地辛和顺铂用法同VD组,观察两组患者的疗效。结果 VP组9例有效,有效率45%,VPH组16例有效,有效率61.5%,两组比较,疗效有显著差异(P<0.05)。结论羟基喜树碱联合长春地辛及顺铂治疗晚期非小细胞肺癌,疗效好,毒副反应不大,价格适中,值得基层医院试用。
Objective To make a study on the effectiveness of hydroxycamtothecine（HCPT） combined with vindesine（VDS） and cisplatin（PDD） in the treatment of patients with advanced non-small cell lung cancer（NSCLC）.Methods 46 patients receiving chemotherapy were randomly divided into two groups：VP（VDS 50mg on days 1,8＋PDD 40mg on days 1-3） group 20 cases and HVP（HCTP 10mg days1-5＋VP）group 26 cases.Results 9 cases（45%） were effective in VP group,but 16 cases（61.5%） were effective in HVP group.There was significant difference in two groups（P0.05）.Conclusion HVP regimen for NSCLC was effective、cheap and safe.It was worth using in primary hospital.
出处
《哈尔滨医药》
2010年第5期9-9,11,共2页
Harbin Medical Journal
关键词
羟基喜树碱
非小细胞肺癌
疗效
Hydroxycamtothecine
Non-small cell lung cancer
Effection
