期刊文献+

舒芬太尼复合罗哌卡因应用于妊娠期糖尿病分娩镇痛的临床研究 被引量:10

Clinical study of sufentanil combined ropivacaine for labor pain in gestational diabetes mellitus
下载PDF
导出
摘要 目的:探讨舒芬太尼复合罗哌卡因应用于分娩镇痛对妊娠期糖尿病(gestational diabetes mellitus,GDM)分娩结局及产程中血糖水平的影响。方法:125例GDM产妇,采用舒芬太尼复合罗哌卡因实施腰麻-硬膜外联合(combined spinal-epidural,CSE)分娩镇痛的60例为研究组,未选择分娩镇痛的65例为对照组,评定舒芬太尼复合罗哌卡因的镇痛效果并比较两组产妇的分娩结局及血糖水平。结果:研究组于麻醉成功后10min内均达到镇痛效果;研究组第一产程活跃期时限长于对照组(P<0.05),产程中剖宫产率低于对照组(P<0.05),产程中血糖水平低于对照组(P<0.05)。结论:舒芬太尼复合罗哌卡因应用于GDM的分娩镇痛效果确切,有益于产程中血糖水平的稳定,降低剖宫产率。 AIM:To evaluate the effect of sufentanil combined ropivacaine for labor anesthesia on labor outcome and blood glucose during childbirth of gestational diabetes mellitus.METHODS:125 cases of gestational diabetes mellitus who selected vaginal delivery,60 cases in study group received sufentanil combined ropivacaine for pain relief during childbirth,65 cases in control group without any pain relief during childbirth,labor outcome and blood glucose during childbirth were compared between two groups.RESULTS:Patients in study group felt pain relief in ten minutes since receiving CSEA.The duration of active phase in the first stage in study group was significantly longer than that of control group(P0.05).Patients who received cesarean section(CS)in study group were lower than that of control group(P0.05).Blood glucose during childbirth was significantly lower in study group than that of control group(P 0.05).CONCLUSION:Sufentanil combined ropivacaine could alleviate labor pain,stabilize blood glucose and reduce CS rate during childbirth in GDM patients.
出处 《中国临床药理学与治疗学》 CAS CSCD 2010年第8期920-923,共4页 Chinese Journal of Clinical Pharmacology and Therapeutics
基金 广东省科技计划项目资助(2007B031501007)
关键词 舒芬太尼 罗哌卡因 分娩镇痛 妊娠期糖尿病 分娩结局 血糖 Sufentanil Ropivacaine Labor anesthesia Gestational diabetes mellitus Labor outcome Blood glucose
  • 相关文献

参考文献11

  • 1杨慧霞,周世梅.妊娠合并糖尿病[M].中华妇产科学.3版.北京:人民卫生出版社,2004:549-560
  • 2Standl T. Combined spinal-epidural anaesthesia for pain relief in obsletric patients[J]. Anasthesiol Intensivmed Notfallmed Schmerzther, 2007,42 (5): 342-349.
  • 3Missant C, Teunkenst A, Vandermeersch E, et al . Patient controlled epidural analgesia following combined spinal-epidural analgesia in labour: the effects of adding a continuous epidural infusion[J]. Anaesth Intensive Care,2005,33 (4) :452--456.
  • 4蔡晓雷,钟惠珍,甘果,袁力勇,黄建平,方春峰.罗哌卡因蛛网膜下隙阻滞分娩镇痛的剂量-效应关系[J].中国临床药理学与治疗学,2009,14(1):90-93. 被引量:11
  • 5张渺,杨慧霞,李海燕,史彗星,曲元.蛛网膜下腔阻滞加硬膜外阻滞与单纯硬膜外阻滞对产程进展影响的分析[J].中华妇产科杂志,2005,40(6):365-368. 被引量:64
  • 6Zhang J, Troendle JF, Yancey MK. Reassessing the labor curve [J].Am J Obstet Gynecol, 2002, 187(4): 824- 828.
  • 7彭朗鸣,尹春艳,黄小鹏.持续硬膜外阻滞分娩镇痛的激素变化对宫缩的影响[J].中国优生与遗传杂志,2007,15(6):54-55. 被引量:14
  • 8Capogna G, Camorcia M, Columb MO. Minimum analgesic doses of fentanyl and sufentanil for epidural analgesia in the first stage of labor[J]. Anesth Analg,2003,96(4): 1178--1182.
  • 9Toledo P, McCarthy RJ, Ebarvia MJ,et al. A retrospective case controlled study of the association between request to discontinue second stage labor epidural analgesia and risk of instrumental vaginal delivery[J]. Int J Obstet Anesth, 2008,17(4):304 --308.
  • 10Lattermann R, Belohlavek G, Wittmann S, et al. The anticatabolic effect of neuraxial blockade after hip surgery[J]. Anesth Analg,2005,101(4): 1202 -1208.

二级参考文献24

  • 1吴超英,任利容,王泽华.罗哌卡因用于分娩镇痛对产程和分娩方式的影响[J].中华妇产科杂志,2005,40(6):369-371. 被引量:95
  • 2尹春艳,张智,陈健飞,李泽泳,陈月秀,刘婷婷,陈晓艳.用系统思想探讨硬膜外阻滞分娩镇痛对产后抑郁症的影响[J].现代医院,2006,6(11):12-15. 被引量:4
  • 3尹春艳,周敬珍,吕小燕,黄小鹏,何桂华,陈建飞.持续硬膜外阻滞分娩镇痛的子宫收缩和产程特点[J].南方医科大学学报,2006,26(11):1563-1567. 被引量:32
  • 4Camorcia M, Capogna G, Columb MO. Minimum local analgesic doses of ropivacaine, levobupivacaine, and bupivacaine for intrathecal labor analgesia [ J ]. Anesthesiology, 2005,102(3) :646 - 650.
  • 5Sia AT, Goy RW, Lira Y,et al.A comparison of median effective doses of intrathecal levobupivacaine and ropivacaine for labor analgesia [ J ]. Anesthesiology, 2005, 102 (3) : 651 - 656.
  • 6Van de Velde M, Dreelinck R, Dubois J, et al. Determination of the full dose-response relation of intrathecal bupivacaine, levobupivacaine, and ropivacaine, combined with sufentanil, for labor analgesia[ J]. Anesthesiology, 2007, 106( 1 ) : 149 - 156.
  • 7Camorcia M, Capogna G, Lyons G, et al. The relative motor blocking potencies of intrathecal ropivacaine: effects of concentration[ J ]. Anesth Analg, 2004, 98 (6) : 1779 - 1782.
  • 8裘福荣,黄晓晖,李娟.药物效应动力学及受体动力学[M]//孙瑞元,郑青山,主编.数学药理学新论.北京:人民卫生出版社,2004:205-206.
  • 9Columb MO, Lyons G. Determination of the minimum local analgesic concentrations of epidural bupivacaine and lidocaine in labor[J]. Anesh Analg, 1995, 81 (4): 833 - 837.
  • 10Capogna G, Parpaglioni R, Lyons G, et al. Minimum analgesic dose of epidural sufentanil for first-stage labor analgesia[J]. Anesthesiology, 2001,94(5) :740 - 744.

共引文献92

同被引文献86

引证文献10

二级引证文献46

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部