1Lazarou J,Pomeranz BH,Corey PN.Incidence of adverse drug reactions in hospitalised patients:a meta-analysis of prospective studies[J].JAMA,1998,279(15):1200-1205.
2Mangoni AA,Jackson SH.Age-related changes in pharmacokinetics and pharmacodynamics:basic principles and practical applications[J].Br J Clin Pharmacol,2004,57(1):6-14.
3Woodhouse KW,O′Mahony MS.Frailty and ageing[J].Age Ageing,1997,26(4):245-246.
4Spinewine A,Schmader KE,Barber N,et al.Appropriate prescribing in elderly people:how well can it be measured and optimised[J]? Lancet,2007,370(9582):173-184.
5Lindley CM,Tully MP,Paramsothy V,et al.Inappropriate medication is a major cause of adverse drug reactions in elderly patients[J].Age Ageing,1992,21(4):294-300.
6Lau DT,Kasper JD,Potter DE,et al.Hospitalization and death associated with potentially inappropriate medication prescriptions among elderly nursing home residents[J].Arch Intern Med,2005,165(1):68-74.
7Gurwitz JH,Field TS,Avorn J,et al.Incidence and preventability of adverse drug events in nursing homes[J].Am J Med,2000,109(2):87-94.
8Klarin I,Wimo A,Fastbom J.The association of inappropriate drug use with hospitalisation and mortality:a population-based study of the very old[J].Drugs Aging,2005,22(1):69-82.