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左氧氟沙星注射液与阿奇霉素注射液治疗社区获得性肺炎的药物最小成本分析 被引量:1

Cost-Minimization Analysis of Levofloxacin vs.Azithromycin in the Treatment of Community Acquired Pneumonia
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摘要 目的 评价左氧氟沙星注射液与阿奇霉素注射液治疗社区获得性肺炎的药物经济学效果,以促进合理用药,降低医疗费用.方法 采用随机分组的研究,选择社区获得性肺炎病例84例,分别给予左氧氟沙星注射液(A组)、阿奇霉素注射液(B组)治疗.观察两组的临床疗效、安全性,并进行药物经济学分析.结果 左氧氟沙星注射液组和阿奇霉素注射液组治疗社区获得性肺炎的有效率分别为86.67%和94.87%(P>0.05),平均成本分别为308.79±84.60元和439.45±62.04元,两组比较差异有统计学意义(P<0.05).结论 以药物经济学的观点分析,左氧氟沙星治疗方案是一种有效、经济的选择. Objective To evaluate the economic effects of levofloxacin and azithromycin for community acquired pneumonia in order to promote clinical rational drug use and save money. Methods 84 patients with community acquired pneumonia were randomly assigned to receive levofloxacin for injection (Group A) or azithromycin injection (Group B ), respectively. In both groups the observation of curative effects and safety and the pharmacoeconomic analysis were conducted. Results The effective rates of two groups were 86.67% and 94. 87% ( P 〉 0. 05 ), respectively. The average cost was 308. 79 ± 84. 60 yuan in Group A versus 439.45 ± 62.04 yuan in Group B, and there is significant difference between them (P 〈 0. 05 ). conclusion Levofloxacin injection is more effective and lower cost in treating community acquired pneumonia.
机构地区 永州市人民医院
出处 《中外医学研究》 2010年第22期1-3,共3页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 左氧氟沙星注射液 阿奇霉素注射液 社区获得性肺炎 药物最小成本 Levofloxacin Azithromycin Community acquired pneumonia Cost - minimization analysis
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