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缬沙坦联合吲哒帕胺治疗老年高血压81例临床效果观察 被引量:9

Effect of combined therapy with valsartan and indapamide on senile hypertension
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摘要 目的:探讨缬沙坦联合吲哒帕胺治疗老年高血压病的临床效果。方法:选择我院2008年1月~2010年1月老年高血压患者81例,随机分为观察组41例和对照组40例。所有患者均停用其他降压药物1周以上。对照组患者给予缬沙坦,每天80 mg;观察组在对照组用药基础上,给予吲达帕胺缓释片,每次1.25 mg,每天1次。两组患者共治疗4周。结果:观察组治疗后舒张压、收缩压分别和对照组治疗后比较,差异有统计学意义(P<0.05);两组患者总有效率比较,差异有统计学意义(P<0.05)。结论:缬沙坦联合吲哒帕胺治疗老年高血压病临床效果显著,值得借鉴。 Objective: To explore the effect of combined therapy with valsartan and indapamide on senile hypertension.Methods: A total of 81 cases with senile hypertension admitted from Jan.2008 to Jan.2010 were randomly divided into observation group(41 cases) and control group(40 cases).All patients had drug withdrawal for more than 1 week.Patients in control group were treated with valsartan 80 mg per day for 4 weeks,and observation group with indapamide 1.25 mg per day for 4 weeks.Results: Diastolic and systolic pressure and total efficiency in observation group were significantly different from those in control group(P0.05).Conclusions: Combined therapy with valsartan and indapamide is effective on treatment of senile hypertension.
作者 王栋
出处 《海南医学院学报》 CAS 2010年第10期1307-1308,1313,共3页 Journal of Hainan Medical University
基金 海南医学院科研基金资助学报项目(0020100359)~~
关键词 高血压 老年 缬沙坦 吲达帕胺 Hypertension Senile Valsartan Indapamide
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