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塌陷性肾小球病三例临床及病理报告 被引量:2

Collapsing glomerulopathy:a clinical and pathological report of 3 cases
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摘要 目的了解塌陷性肾小球病在中国汉族人群中的发生情况及临床病理特点。方法对1996年1月至1998年3月832例肾活检患者的血液生化学指标,肾活检穿刺标本的光镜、免疫荧光、透射电镜等病理学检查结果进行分析,对3例患者行HIV病毒学检查。结果塌陷性肾小球病发生率占局灶节段性肾小球硬化的176%,病理改变、临床特征及预后与国外报道类似。结论塌陷性肾小球病具有特殊的临床病理特征,预后差,是一种值得重视的病理临床新概念。 Objective To investigate incidence,clinical and pathologic characteristics of collapsing glomerulopathy among Chinese han population. Methods The complete clinical informations of 832 cases,from 19961998,were analyzed,including serum index,results of specimen of kidney etc. Results About 176% focal segmental glomerulosclerosis were collapsing glomerulopathy.Its clinical pathologic features and prognosis were similar to foreign reports. Conclusion Collapsing glomerulopathy has special clinicopathologic characteristics and poor prognosis.It is a new clinicopathologic concept worth of noticing.
出处 《中华肾脏病杂志》 CAS CSCD 北大核心 1999年第3期152-154,共3页 Chinese Journal of Nephrology
关键词 肾小球疾病 病理 病例报告 ClinicPathologyCollapsingglomerulopathy
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参考文献2

  • 1Yang Y,JASN,1997年,8卷,546A页
  • 2Weis M A,Am J Kideny Dis,1986年,7卷,20页

同被引文献8

  • 1章友康 王海燕 等.黄芪和当归治疗三种不同病理类型肾炎的实验研究[J].中华内科杂志,1986,25(4):222-222.
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  • 5Singh HK, Baldree LA, Hogan SL,Idiopathic collapsing glomerulopathy in children. Pediatr Nephrol,2000,14: 132-137.
  • 6Shankland SJ, Eitner-F, Hudkins KL,et al. Differential expression of cyclin dependent kinase inhibitors in human glomerular disease. Kidney Int,2000,58:674-683.
  • 7Moudgil A, Nast CC, Bagga A, et al. Association parvovirus B19 infection with idiopathic collapsing glmerulopathy. Kidney Int, 2001,59:2126-2133.
  • 8Detwiler RK, Falk RJ, Hogan SL, et al. Collapsing glomerulopathy: a clinically and pathologically distinct variant of focal segmental glomerulosclerosis. Kidney Int, 1994 45:1416-1424.

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