摘要
目的研究枳实中的多甲氧基黄酮类化合物。方法对枳实95%乙醇提取物的醋酸乙酯部分和正丁醇部分进行色谱分离,通过核磁共振和质谱分析鉴定其化合物的结构。结果从枳实中分离鉴定出4个多甲氧基黄酮类化学成分,分别为桔皮晶(Tangeretin,Ⅰ),蜜桔黄素(Nobiletin,Ⅱ),4',5,7,8-四甲氧基黄酮(4',5,7,8-Tetramethoxyflavone,Ⅲ),5-降甲基蜜桔黄素(5-Demethylnobiletin,Ⅳ)。结论Ⅰ,Ⅱ,Ⅲ,Ⅳ化合物均为首次从枳实中分离得到。
Objective To investigate the chemical constituents of Fructus Aurantii Immaturus. Methods The constituents of the EtOAc-solube portion and normal butanol solube portion in the 95% ethanol extract were isolated and purified by means of chromatography. Compounds were identified by 1H-NMR,13C-NMR and MS. Results Four polymethoxylated flavonoids were isolated and identified as Tangeretin （ Ⅰ） ,Nobiletin （ Ⅱ） ,4＇,5,7,8-Tetramethoxyflavone （ Ⅲ） and 5-Demethylnobiletin （ Ⅳ） . Conclusion CompoundsⅠ-Ⅳ were isolated from Fructus Aurantii Immaturus for the first time.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2010年第10期2469-2470,共2页
Lishizhen Medicine and Materia Medica Research
基金
浙江省自然科学基金(No.Y4090121)
关键词
枳实
多甲氧基黄酮
化学成分
Fructus Aurantii Immaturus
Polymethoxylated flavonoids
Chemical constituents
