摘要
中成药对治疗类风湿关节炎有独到临床作用,中成药治疗类风湿关节炎的实验研究也逐步拓展与深入,回顾近3年来丸剂、胶囊、颗粒剂、片剂、注射液、口服液、浸膏、涂膜搽剂、药酒、合剂等制剂形态的中成药的实验研究,可见中成药对类风湿关节炎有不同程度的免疫调控、消肿镇痛、内分泌调节、抑制血管翳形成等作用,进而改善其症状,控制病情进展,并对联用的激素等药物有增效减毒的效果;但动物模型选取、安全性研究、有效成分及制剂工艺探讨等薄弱方面有待更进一步完善。
Chinese patent medicines have distinct effect on rheumatoid arthritis. Experimental researches in Chinese patent medicines for rheumatoid arthritis get more expanded and deep recently. Studies of preparation forms such as pilulae, capsule, drug granules, tabella, injection, oral solutions, extract, linimentum, medicinal liquor and composition for rheumatoid arthritis are the focus of this review. It can be seen from these researches that the functions of Chinese traditional patent medicines are immunoregulation, detumescence, odynolysis, endocrine regulation, and pannus forming inhibition, and subsequently to ameliorate symptoms, manage pathological progress, act as synergist and attenuation medicines with glucocorticosteroid combined. However, researches in animal model, safety, effective ingredient, pharmaceutics technology need further improvement.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2010年第11期1846-1849,共4页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家自然科学基金面上项目(No.30772809)
天津市应用基础研究计划面上项目(No.06YFJMJC09600)~~
关键词
中成药
类风湿关节炎
实验研究
Chinese traditional patent medicine
Rheumatoid arthritis
Experimental research