摘要
目的:分析三氧化二砷治疗多发性骨髓瘤的作用机理。方法:综合分析有关三氧化二砷治疗多发性骨髓瘤的文献。结果与结论:三氧化二砷治疗多发性骨髓瘤的机理主要包括:抑制多发性骨髓细胞的增殖,并促进其凋亡;改变多发性骨髓性细胞基因表达并抑制其新生血管;影响其基质细胞增殖和分泌。
Objective： To analyse the mechanism of arsenic trioxide treatment of multiple myeloma. Methods： A comprehensive analysis of the literature about arsenic trioxide on the treatment of multiple myeloma. Results and conclusion： The arsenic trioxide treatment of multiple myeloma mechanism was as follows： multiple bone marrow cell proliferation, and promote its apoptosis, change the multiple myeloma cells gene expression and its new blood vessels, Affect the secretion of cell proliferation and matrix.
出处
《中医学报》
CAS
2010年第6期1052-1054,共3页
Acta Chinese Medicine
基金
浙江省自然科学基金(编号:Y2101416)
