摘要
目的探讨头孢曲松钠联合多西环素治疗男性尿道混合性感染的疗效与安全性。方法 106例患者随机分为治疗组和对照组,各53例;治疗组:采用头孢曲松钠联合多西环素治疗,即有并发症者予头孢曲松钠250mg肌注,1次/d,无并发症者予头孢曲松钠250mg单剂一次肌注,同时口服盐酸多西环素100mg,2次/d。对照组:仅给予头孢曲松钠治疗,方法同治疗组。两组每日治疗者疗程均为10天。结果两组治愈率分别为84.91%和54.72%,差异有统计学意义(P<0.005)。且两组不良反应近似,均未发生严重副作用。结论头孢曲松钠联合多西环素治疗男性尿道混合性感染效果显著。
Objective To investigate the curative effect and safety of ceftriaxone sodium combining with doxycycline treat male urethra mixed infections. Methods One hundred and six patients were randomly divided into two groups, each group contained 53 patients. The treatment group were treated with the methods of ceftriaxone so- dium combining with doxycycline, patients with complications were treated by intramuscular injection ceftriax- one sodium 250rag once a day, patients without complications were treated by intramuscular injection ceftriax- one sodium 250mg single dosage once, while taked doxycycline 100rag twice everyday. The control group were treated by ceftriaxone sodium only, the treatment method was together with the treatmenl group. The course of treatment was 10 days to everyday treatment. Results The curative rates of two groups were 84.91% and 54.72% respectively, and difference had the sense of statistics ( P 〈 0. 005 ), and 2 groups of bad reactions were similar, serious side-effect did not happen. Conclusion Ceftriaxone sodium combining with doxycycline treatments male urethra mixed infections cound raise remarkable the curative effect.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2010年第11期1037-1038,共2页
The Chinese Journal of Dermatovenereology