摘要
目的:观察盐酸法舒地尔治疗颅脑损伤患者的疗效。方法:将384例颅脑损伤患者按照随机数字表法分成2组,治疗组192例,在常规治疗基础上应用盐酸法舒地尔30mg加入0.9%氯化钠注射液100mL中静脉滴注,2次·d-1,连用14d;对照组192例,仅行常规治疗。2组于伤后3个月按格拉斯哥昏迷量表(GCS)评分评定预后。结果:治疗组与对照组的预后良好率分别为70.83%、56.77%,2组比较差异有统计学意义(P<0.05)。结论:盐酸法舒地尔可促进颅脑损伤患者脑功能恢复,改善其预后。
OBJECTIVE：To observe the therapeutic efficacy of fasudil for patients with craniocerebral injury. METHODS：384 patients with craniocerebral injury were randomly divided into 2 groups. 192 cases in treatment group were treated with fasudil injection 30 mg dissolved in 0.9% sodium chloride injection 100 mL twice a day intravenously for 14 days besides the routine treatment, and 192 cases in control group were only given conventional therapy. The clinical prognosis of patients was evaluated between 2 groups after 3 months since being injured according to GCS scores. RESULTS：The rate of good recovery was 70.83% for treatment group and 56.77% for control group. There was statistical significance between 2 groups（P0.05）. CONCLUSION：Fasudil has significant efficacy on accelerating the recovery of cerebral function in craniocerebral trauma patients and improving prognosis.
出处
《中国药房》
CAS
CSCD
北大核心
2010年第42期3996-3997,共2页
China Pharmacy
